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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACVR1B
All Species:
22.73
Human Site:
T206
Identified Species:
50
UniProt:
P36896
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36896
NP_004293.1
505
56807
T206
V
Q
R
T
V
A
R
T
I
V
L
Q
E
I
I
Chimpanzee
Pan troglodytes
XP_509071
476
53363
T206
V
Q
R
T
V
A
R
T
I
V
L
Q
E
I
I
Rhesus Macaque
Macaca mulatta
XP_001091363
505
56901
T206
V
Q
R
T
V
A
R
T
I
V
L
Q
E
I
I
Dog
Lupus familis
XP_543663
484
54936
V200
G
K
G
R
F
G
E
V
W
R
G
R
W
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61271
505
56682
T206
V
Q
R
T
V
A
R
T
I
V
L
Q
E
I
I
Rat
Rattus norvegicus
P80202
505
56786
T206
V
Q
R
T
V
A
R
T
I
V
L
Q
E
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520990
481
54192
V197
G
K
G
R
F
G
E
V
W
R
G
K
W
R
G
Chicken
Gallus gallus
Q05438
502
56748
Q203
V
Q
R
T
I
A
K
Q
I
Q
M
V
K
Q
I
Frog
Xenopus laevis
P27041
511
57917
F200
D
I
K
A
R
G
R
F
G
C
V
W
K
A
R
Zebra Danio
Brachydanio rerio
NP_571065
505
56615
T206
V
Q
R
T
V
A
R
T
I
V
L
Q
E
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20792
669
74988
L268
P
N
N
M
K
D
M
L
D
V
L
E
E
T
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
99.5
94
N.A.
98.2
98.8
N.A.
67.5
50.2
31.1
78.2
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
100
93
99.8
94.6
N.A.
99.4
99.5
N.A.
78.6
65.3
47.9
87.1
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
46.6
6.6
100
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
13.3
73.3
26.6
100
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
64
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
19
0
0
0
0
10
64
0
0
% E
% Phe:
0
0
0
0
19
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
19
0
19
0
0
28
0
0
10
0
19
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
64
0
0
0
0
55
64
% I
% Lys:
0
19
10
0
10
0
10
0
0
0
0
10
19
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
64
0
0
0
0
% L
% Met:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
64
0
0
0
0
0
10
0
10
0
55
0
10
0
% Q
% Arg:
0
0
64
19
10
0
64
0
0
19
0
10
0
19
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
64
0
0
0
55
0
0
0
0
0
10
0
% T
% Val:
64
0
0
0
55
0
0
19
0
64
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
19
0
0
10
19
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _