KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB5
All Species:
23.33
Human Site:
S252
Identified Species:
57.04
UniProt:
P36952
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36952
NP_002630.2
375
42100
S252
K
I
E
K
Q
L
N
S
E
S
L
S
Q
W
T
Chimpanzee
Pan troglodytes
XP_523955
404
45178
S281
K
I
E
K
Q
L
N
S
E
S
L
S
Q
W
T
Rhesus Macaque
Macaca mulatta
XP_001090087
375
42169
S252
K
I
E
K
Q
L
N
S
E
S
L
L
Q
W
T
Dog
Lupus familis
XP_533382
823
92665
S264
K
V
E
Q
Q
L
N
S
E
T
L
L
Q
W
T
Cat
Felis silvestris
Mouse
Mus musculus
P70124
375
42093
P252
K
I
E
Q
Q
L
N
P
E
T
L
L
Q
W
T
Rat
Rattus norvegicus
P70564
375
42045
P252
K
I
E
K
Q
L
N
P
E
T
L
L
Q
W
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510853
375
41689
S252
K
V
E
K
Q
L
S
S
E
T
L
L
D
W
T
Chicken
Gallus gallus
O73790
410
47365
Y280
Q
L
E
R
E
L
T
Y
E
R
L
S
E
W
A
Frog
Xenopus laevis
Q6GLQ1
383
43398
F252
K
L
E
Q
D
M
T
F
E
K
Y
A
Q
W
T
Zebra Danio
Brachydanio rerio
NP_001009892
384
43337
Y257
K
L
E
R
A
L
T
Y
E
K
L
M
E
W
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
98.6
42.2
N.A.
89
88
N.A.
78.9
35.6
53.2
37.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.3
98.9
44.3
N.A.
96.8
95.7
N.A.
90.1
57.7
74.9
63.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
80
N.A.
66.6
40
40
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
86.6
73.3
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
100
0
10
0
0
0
100
0
0
0
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
90
0
0
50
0
0
0
0
0
20
0
0
0
0
0
% K
% Leu:
0
30
0
0
0
90
0
0
0
0
90
50
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
30
70
0
0
0
0
0
0
0
70
0
0
% Q
% Arg:
0
0
0
20
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
50
0
30
0
30
0
0
0
% S
% Thr:
0
0
0
0
0
0
30
0
0
40
0
0
0
0
90
% T
% Val:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% W
% Tyr:
0
0
0
0
0
0
0
20
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _