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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2I
All Species:
33.03
Human Site:
T81
Identified Species:
55.9
UniProt:
P36954
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36954
NP_006224.1
125
14523
T81
Q
D
P
T
L
P
R
T
E
D
H
P
C
Q
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_867729
162
18139
T81
Q
D
P
T
L
P
R
T
E
D
H
P
C
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQZ7
108
12312
P68
N
V
D
S
T
A
E
P
C
P
K
C
E
H
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423952
125
14361
T81
Q
D
P
T
L
P
R
T
E
D
H
P
C
Q
K
Frog
Xenopus laevis
NP_001089293
125
14410
T81
Q
E
P
T
L
P
R
T
E
D
H
P
C
S
K
Zebra Danio
Brachydanio rerio
NP_001006013
126
14576
T82
Q
D
P
T
L
P
R
T
E
D
H
P
C
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36958
129
15079
T85
S
D
P
T
L
P
R
T
E
D
H
A
C
P
K
Honey Bee
Apis mellifera
XP_396002
130
15292
T86
S
D
P
T
L
P
R
T
E
D
H
P
C
P
K
Nematode Worm
Caenorhab. elegans
NP_505062
167
19316
T123
H
D
P
T
L
P
K
T
E
E
H
Q
C
P
V
Sea Urchin
Strong. purpuratus
XP_788078
130
15070
T86
A
D
P
T
L
P
R
T
E
D
H
P
C
E
M
Poplar Tree
Populus trichocarpa
XP_002312337
114
13195
V74
T
L
P
R
T
K
A
V
T
C
T
V
C
K
H
Maize
Zea mays
NP_001150634
114
12939
S73
P
T
L
P
R
T
K
S
V
R
C
S
S
C
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188323
114
13258
V74
T
L
P
R
T
K
A
V
R
C
S
K
C
Q
H
Baker's Yeast
Sacchar. cerevisiae
P27999
122
14270
R81
E
C
P
K
C
H
S
R
E
N
V
F
F
Q
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
69.1
N.A.
25.6
N.A.
N.A.
N.A.
94.4
93.5
92.8
N.A.
73.6
72.3
47.9
79.2
Protein Similarity:
100
N.A.
N.A.
70.9
N.A.
40.7
N.A.
N.A.
N.A.
97.5
98.4
95.2
N.A.
82.9
83.8
61
87.6
P-Site Identity:
100
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
N.A.
100
86.6
93.3
N.A.
80
86.6
60
80
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
6.6
N.A.
N.A.
N.A.
100
93.3
93.3
N.A.
80
86.6
73.3
86.6
Percent
Protein Identity:
51.2
53.6
N.A.
58.4
41.6
N.A.
Protein Similarity:
72.8
71.2
N.A.
74.4
60
N.A.
P-Site Identity:
13.3
0
N.A.
20
20
N.A.
P-Site Similarity:
20
13.3
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
15
0
0
0
0
8
0
0
0
% A
% Cys:
0
8
0
0
8
0
0
0
8
15
8
8
79
8
0
% C
% Asp:
0
58
8
0
0
0
0
0
0
58
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
8
0
72
8
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
8
0
0
0
0
8
0
0
0
0
65
0
0
8
15
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
15
15
0
0
0
8
8
0
8
50
% K
% Leu:
0
15
8
0
65
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
0
86
8
0
65
0
8
0
8
0
50
0
29
8
% P
% Gln:
36
0
0
0
0
0
0
0
0
0
0
8
0
36
0
% Q
% Arg:
0
0
0
15
8
0
58
8
8
8
0
0
0
0
0
% R
% Ser:
15
0
0
8
0
0
8
8
0
0
8
8
8
8
8
% S
% Thr:
15
8
0
65
22
8
0
65
8
0
8
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
15
8
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _