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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2I
All Species:
28.79
Human Site:
Y44
Identified Species:
48.72
UniProt:
P36954
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36954
NP_006224.1
125
14523
Y44
Y
A
C
R
N
C
D
Y
Q
Q
E
A
D
N
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_867729
162
18139
Y44
Y
A
C
R
N
C
D
Y
Q
Q
E
A
D
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQZ7
108
12312
V31
A
C
N
T
C
P
Y
V
H
N
I
T
R
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423952
125
14361
Y44
Y
A
C
R
N
C
D
Y
Q
Q
E
A
D
S
S
Frog
Xenopus laevis
NP_001089293
125
14410
Y44
Y
A
C
R
N
C
D
Y
Q
Q
E
A
D
N
S
Zebra Danio
Brachydanio rerio
NP_001006013
126
14576
Y45
Y
A
C
R
N
C
D
Y
Q
Q
E
A
D
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36958
129
15079
Y48
Y
A
C
R
N
C
D
Y
K
Q
E
A
D
S
N
Honey Bee
Apis mellifera
XP_396002
130
15292
F49
Y
A
C
R
N
C
D
F
K
Q
L
A
D
S
N
Nematode Worm
Caenorhab. elegans
NP_505062
167
19316
H86
Y
S
C
R
N
C
E
H
R
E
V
A
A
N
P
Sea Urchin
Strong. purpuratus
XP_788078
130
15070
Y49
Y
A
C
R
N
C
D
Y
Q
Q
E
A
D
N
A
Poplar Tree
Populus trichocarpa
XP_002312337
114
13195
I37
R
N
C
D
H
Q
E
I
A
D
D
N
C
V
Y
Maize
Zea mays
NP_001150634
114
12939
E36
C
R
N
C
D
H
Q
E
V
A
D
N
N
C
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188323
114
13258
V37
R
N
C
D
H
Q
E
V
A
D
N
S
C
V
Y
Baker's Yeast
Sacchar. cerevisiae
P27999
122
14270
Y44
E
A
G
S
P
L
V
Y
R
H
E
L
I
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
69.1
N.A.
25.6
N.A.
N.A.
N.A.
94.4
93.5
92.8
N.A.
73.6
72.3
47.9
79.2
Protein Similarity:
100
N.A.
N.A.
70.9
N.A.
40.7
N.A.
N.A.
N.A.
97.5
98.4
95.2
N.A.
82.9
83.8
61
87.6
P-Site Identity:
100
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
N.A.
93.3
100
100
N.A.
80
66.6
46.6
93.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
N.A.
100
100
100
N.A.
100
93.3
80
100
Percent
Protein Identity:
51.2
53.6
N.A.
58.4
41.6
N.A.
Protein Similarity:
72.8
71.2
N.A.
74.4
60
N.A.
P-Site Identity:
6.6
0
N.A.
6.6
20
N.A.
P-Site Similarity:
26.6
20
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
65
0
0
0
0
0
0
15
8
0
65
8
0
8
% A
% Cys:
8
8
79
8
8
65
0
0
0
0
0
0
15
8
0
% C
% Asp:
0
0
0
15
8
0
58
0
0
15
15
0
58
0
0
% D
% Glu:
8
0
0
0
0
0
22
8
0
8
58
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
15
8
0
8
8
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
15
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
15
0
65
0
0
0
0
8
8
15
8
43
22
% N
% Pro:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
15
8
0
43
58
0
0
0
0
0
% Q
% Arg:
15
8
0
65
0
0
0
0
15
0
0
0
8
0
0
% R
% Ser:
0
8
0
8
0
0
0
0
0
0
0
8
0
22
36
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% T
% Val:
0
0
0
0
0
0
8
15
8
0
8
0
0
15
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
65
0
0
0
0
0
8
58
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _