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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINF1
All Species:
11.52
Human Site:
S374
Identified Species:
28.15
UniProt:
P36955
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36955
NP_002606.3
418
46342
S374
D
G
A
G
T
T
P
S
P
G
L
Q
P
A
H
Chimpanzee
Pan troglodytes
XP_001154841
418
46272
S374
D
G
A
G
T
T
P
S
P
G
L
Q
P
A
H
Rhesus Macaque
Macaca mulatta
XP_001117361
237
26773
L201
E
G
E
V
T
K
S
L
Q
E
T
M
D
Y
H
Dog
Lupus familis
XP_854003
491
54935
A396
A
G
V
E
A
A
A
A
T
G
T
A
M
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P97298
417
46216
S373
E
G
A
G
S
S
P
S
P
G
L
Q
P
V
R
Rat
Rattus norvegicus
P05544
413
46259
A371
T
G
T
E
A
T
A
A
T
G
V
A
T
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507178
417
46106
S373
D
G
V
G
D
A
P
S
P
A
L
L
P
A
R
Chicken
Gallus gallus
XP_001234865
416
46487
N372
D
G
E
K
S
T
P
N
P
G
V
N
A
A
R
Frog
Xenopus laevis
NP_001085983
409
46170
P363
E
D
G
A
E
T
A
P
K
A
E
A
S
S
R
Zebra Danio
Brachydanio rerio
NP_001004539
406
44935
S362
P
E
G
A
E
Y
A
S
T
T
P
S
A
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
53.8
27.7
N.A.
85.8
29.4
N.A.
77.5
62.9
56.2
38.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
55.5
44.4
N.A.
93.7
51.2
N.A.
88
80.3
74.1
59.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
13.3
N.A.
66.6
20
N.A.
60
46.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
26.6
N.A.
86.6
33.3
N.A.
60
66.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
30
20
20
20
40
20
0
20
0
30
20
40
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
10
0
0
10
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
30
10
20
20
20
0
0
0
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
80
20
40
0
0
0
0
0
60
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
40
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% N
% Pro:
10
0
0
0
0
0
50
10
50
0
10
0
40
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
30
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% R
% Ser:
0
0
0
0
20
10
10
50
0
0
0
10
10
20
0
% S
% Thr:
10
0
10
0
30
50
0
0
30
10
20
0
10
10
0
% T
% Val:
0
0
20
10
0
0
0
0
0
0
20
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _