Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLST All Species: 13.94
Human Site: S17 Identified Species: 23.59
UniProt: P36957 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36957 NP_001924.2 453 48729 S17 R A F S R S L S A F Q K G N C
Chimpanzee Pan troglodytes XP_510068 453 48665 S17 R A F S R S L S A F Q K G N C
Rhesus Macaque Macaca mulatta XP_001095138 454 48899 A18 A F S R S L S A F Q K G N C P
Dog Lupus familis XP_537510 443 47545 S17 R A F S R S L S A F Q K G S P
Cat Felis silvestris
Mouse Mus musculus Q9D2G2 454 48976 A18 A F S R S L S A F Q K G N C P
Rat Rattus norvegicus Q01205 454 48907 A18 A F S R S L S A F Q K G N C P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012919 461 49264 T20 A L G R S V R T L R Q G N C T
Frog Xenopus laevis NP_001080703 452 48982 P21 L T A L R R G P G E T Q S R P
Zebra Danio Brachydanio rerio NP_958895 458 48679 T17 R S L G R S I T A L R Q G N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392679 444 49066 T24 T R N S I S Q T K V V R S L Y
Nematode Worm Caenorhab. elegans Q19749 507 53448 A25 T T A A I S A A N I G F T Q S
Sea Urchin Strong. purpuratus XP_781522 508 55019 A61 R N I K S S I A F S E G C Q W
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001150636 446 48757 R22 V A T L G L L R S H T H V R N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19262 463 50412 R21 L V K S K V A R N V M A A S F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98 87.4 N.A. 92.5 92.9 N.A. N.A. 72.8 75 73.1 N.A. N.A. 54.2 27.6 55.7
Protein Similarity: 100 99.5 98.4 91.3 N.A. 96.2 96 N.A. N.A. 79.3 83.8 82.5 N.A. N.A. 66.4 44.1 67.5
P-Site Identity: 100 100 0 86.6 N.A. 0 0 N.A. N.A. 6.6 6.6 40 N.A. N.A. 13.3 6.6 13.3
P-Site Similarity: 100 100 13.3 93.3 N.A. 13.3 13.3 N.A. N.A. 13.3 13.3 73.3 N.A. N.A. 26.6 20 33.3
Percent
Protein Identity: N.A. 45.7 N.A. N.A. 42.1 N.A.
Protein Similarity: N.A. 61.3 N.A. N.A. 58.5 N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. 20 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 29 15 8 0 0 15 36 29 0 0 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 29 15 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % E
% Phe: 0 22 22 0 0 0 0 0 29 22 0 8 0 0 8 % F
% Gly: 0 0 8 8 8 0 8 0 8 0 8 36 29 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % H
% Ile: 0 0 8 0 15 0 15 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 8 8 8 0 0 0 8 0 22 22 0 0 0 % K
% Leu: 15 8 8 15 0 29 29 0 8 8 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 0 0 15 0 0 0 29 22 8 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 36 % P
% Gln: 0 0 0 0 0 0 8 0 0 22 29 15 0 15 0 % Q
% Arg: 36 8 0 29 36 8 8 15 0 8 8 8 0 15 0 % R
% Ser: 0 8 22 36 36 50 22 22 8 8 0 0 15 15 15 % S
% Thr: 15 15 8 0 0 0 0 22 0 0 15 0 8 0 8 % T
% Val: 8 8 0 0 0 15 0 0 0 15 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _