KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACVRL1
All Species:
41.82
Human Site:
S266
Identified Species:
76.67
UniProt:
P37023
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37023
NP_000011.2
503
56124
S266
F
I
A
S
D
M
T
S
R
N
S
S
T
Q
L
Chimpanzee
Pan troglodytes
XP_001145379
494
55044
L251
E
I
Y
N
T
V
L
L
R
H
D
N
I
L
G
Rhesus Macaque
Macaca mulatta
XP_001090993
503
56074
S266
F
I
A
S
D
M
T
S
R
N
S
S
T
Q
L
Dog
Lupus familis
XP_534796
504
56421
S267
F
I
A
S
D
M
T
S
R
N
S
S
T
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61288
502
56614
S265
F
I
A
S
D
M
T
S
R
N
S
S
T
Q
L
Rat
Rattus norvegicus
P80203
504
56685
S267
F
I
A
S
D
M
T
S
R
N
S
S
T
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509625
512
57592
S275
F
I
A
S
D
M
T
S
R
H
S
S
T
Q
L
Chicken
Gallus gallus
Q90ZK6
504
56206
S267
F
I
A
S
D
M
T
S
R
N
S
S
T
Q
L
Frog
Xenopus laevis
P27041
511
57917
G253
F
I
A
A
E
K
R
G
S
N
L
E
M
E
L
Zebra Danio
Brachydanio rerio
NP_571420
506
56709
S269
F
M
A
S
D
M
T
S
R
N
S
S
T
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523652
570
64210
S328
F
I
G
S
D
M
T
S
R
N
S
C
T
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09488
636
72217
S329
F
V
A
A
D
I
W
S
E
E
D
S
M
T
K
Sea Urchin
Strong. purpuratus
XP_794984
512
58526
S268
F
F
A
S
D
M
T
S
R
Q
S
C
T
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
98.6
93
N.A.
88.4
89.4
N.A.
58.7
61.3
30.5
59.2
N.A.
47.3
N.A.
31.4
49.6
Protein Similarity:
100
93.2
99.1
95.6
N.A.
93
93.2
N.A.
71.8
74
46.3
70.9
N.A.
61.9
N.A.
47.1
64.8
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
100
33.3
93.3
N.A.
86.6
N.A.
33.3
80
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
100
100
53.3
100
N.A.
86.6
N.A.
53.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
85
16
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% C
% Asp:
0
0
0
0
85
0
0
0
0
0
16
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
0
8
8
0
8
0
8
0
% E
% Phe:
93
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% H
% Ile:
0
77
0
0
0
8
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
8
8
0
0
8
0
0
8
85
% L
% Met:
0
8
0
0
0
77
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
70
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
77
0
% Q
% Arg:
0
0
0
0
0
0
8
0
85
0
0
0
0
0
0
% R
% Ser:
0
0
0
77
0
0
0
85
8
0
77
70
0
0
0
% S
% Thr:
0
0
0
0
8
0
77
0
0
0
0
0
77
8
0
% T
% Val:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _