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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACVRL1
All Species:
48.79
Human Site:
T248
Identified Species:
89.44
UniProt:
P37023
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37023
NP_000011.2
503
56124
T248
R
E
T
E
I
Y
N
T
V
L
L
R
H
D
N
Chimpanzee
Pan troglodytes
XP_001145379
494
55044
S233
V
A
V
K
I
F
S
S
R
D
E
Q
S
W
F
Rhesus Macaque
Macaca mulatta
XP_001090993
503
56074
T248
R
E
T
E
I
Y
N
T
V
L
L
R
H
D
N
Dog
Lupus familis
XP_534796
504
56421
T249
R
E
T
E
I
Y
N
T
V
L
L
R
H
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61288
502
56614
T247
R
E
T
E
I
Y
N
T
V
L
L
R
H
D
N
Rat
Rattus norvegicus
P80203
504
56685
T249
R
E
T
E
I
Y
N
T
V
L
L
R
H
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509625
512
57592
T257
R
E
T
E
L
Y
N
T
V
L
L
R
H
E
N
Chicken
Gallus gallus
Q90ZK6
504
56206
T249
R
E
T
E
L
Y
N
T
V
L
L
R
H
E
N
Frog
Xenopus laevis
P27041
511
57917
T235
C
E
K
E
I
F
T
T
P
G
M
K
H
E
N
Zebra Danio
Brachydanio rerio
NP_571420
506
56709
T251
R
E
T
E
I
Y
N
T
V
L
L
R
H
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523652
570
64210
T310
R
E
T
E
I
Y
S
T
I
L
L
R
H
E
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09488
636
72217
T311
N
E
R
D
V
Y
Q
T
N
M
I
N
H
E
N
Sea Urchin
Strong. purpuratus
XP_794984
512
58526
T250
R
E
T
E
I
Y
N
T
V
M
L
R
H
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
98.6
93
N.A.
88.4
89.4
N.A.
58.7
61.3
30.5
59.2
N.A.
47.3
N.A.
31.4
49.6
Protein Similarity:
100
93.2
99.1
95.6
N.A.
93
93.2
N.A.
71.8
74
46.3
70.9
N.A.
61.9
N.A.
47.1
64.8
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
86.6
86.6
40
93.3
N.A.
80
N.A.
33.3
86.6
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
100
100
66.6
100
N.A.
100
N.A.
66.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
8
0
0
0
39
0
% D
% Glu:
0
93
0
85
0
0
0
0
0
0
8
0
0
54
0
% E
% Phe:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% H
% Ile:
0
0
0
0
77
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
8
8
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
0
16
0
0
0
0
70
77
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
16
8
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
70
0
8
0
0
8
0
0
93
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
77
0
8
0
0
0
0
0
8
0
0
77
0
0
0
% R
% Ser:
0
0
0
0
0
0
16
8
0
0
0
0
8
0
0
% S
% Thr:
0
0
77
0
0
0
8
93
0
0
0
0
0
0
0
% T
% Val:
8
0
8
0
8
0
0
0
70
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
85
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _