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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCNN1A All Species: 0
Human Site: S16 Identified Species: 0
UniProt: P37088 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P37088 NP_001029.1 669 75704 S16 Q D S S P P Q S T P G L M K G
Chimpanzee Pan troglodytes O46547 638 70169 G17 R M E A A T R G G S H L Q A A
Rhesus Macaque Macaca mulatta XP_001103017 669 75686 P16 Q D A S P P Q P T P G L K K G
Dog Lupus familis XP_534912 687 77703 C34 T P T L H D P C S P R L M K G
Cat Felis silvestris
Mouse Mus musculus Q61180 699 78875 P41 Q D L C P P L P M Q G L G K G
Rat Rattus norvegicus P37089 698 78869 P41 Q D P C P P Q P M Q G L G K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512591 607 68526 P10 M T T R R L R P R R Y R P A G
Chicken Gallus gallus Q92075 637 73218 K14 G G S V K A E K M P E G E K T
Frog Xenopus laevis P51167 632 72609 F15 E K E A L I E F F S S Y R E L
Zebra Danio Brachydanio rerio Q708S7 501 57400
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 94.3 83.6 N.A. 79.5 79.9 N.A. 68.3 57.7 55.9 22.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 53.3 96.7 87.6 N.A. 85.4 84.9 N.A. 77.5 71.5 70.5 38.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 80 33.3 N.A. 53.3 60 N.A. 6.6 20 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 86.6 46.6 N.A. 53.3 60 N.A. 20 26.6 26.6 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 20 10 10 0 0 0 0 0 0 0 20 10 % A
% Cys: 0 0 0 20 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 40 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 20 0 0 0 20 0 0 0 10 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 0 0 0 10 10 0 40 10 20 0 60 % G
% His: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 10 0 0 10 0 0 0 0 10 60 0 % K
% Leu: 0 0 10 10 10 10 10 0 0 0 0 60 0 0 10 % L
% Met: 10 10 0 0 0 0 0 0 30 0 0 0 20 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 0 40 40 10 40 0 40 0 0 10 0 0 % P
% Gln: 40 0 0 0 0 0 30 0 0 20 0 0 10 0 0 % Q
% Arg: 10 0 0 10 10 0 20 0 10 10 10 10 10 0 0 % R
% Ser: 0 0 20 20 0 0 0 10 10 20 10 0 0 0 0 % S
% Thr: 10 10 20 0 0 10 0 0 20 0 0 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _