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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCNN1A
All Species:
22.12
Human Site:
T154
Identified Species:
54.07
UniProt:
P37088
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37088
NP_001029.1
669
75704
T154
L
E
E
L
D
R
I
T
E
Q
T
L
F
D
L
Chimpanzee
Pan troglodytes
O46547
638
70169
A155
L
E
L
L
D
E
F
A
R
E
N
I
D
S
L
Rhesus Macaque
Macaca mulatta
XP_001103017
669
75686
T154
L
E
E
L
D
R
I
T
Q
Q
T
L
F
D
L
Dog
Lupus familis
XP_534912
687
77703
T172
L
E
E
L
D
R
I
T
E
Q
T
L
Y
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61180
699
78875
T179
L
E
E
L
D
R
I
T
E
Q
T
L
F
D
L
Rat
Rattus norvegicus
P37089
698
78869
T179
L
E
E
L
D
R
I
T
E
Q
T
L
F
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512591
607
68526
G138
S
R
P
R
S
R
R
G
L
G
S
P
L
P
H
Chicken
Gallus gallus
Q92075
637
73218
T146
L
D
E
L
D
Q
I
T
H
Q
T
L
L
D
L
Frog
Xenopus laevis
P51167
632
72609
K144
I
P
N
N
Q
R
V
K
R
D
R
A
G
L
P
Zebra Danio
Brachydanio rerio
Q708S7
501
57400
L32
V
F
A
H
T
S
T
L
H
G
I
S
H
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
94.3
83.6
N.A.
79.5
79.9
N.A.
68.3
57.7
55.9
22.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
53.3
96.7
87.6
N.A.
85.4
84.9
N.A.
77.5
71.5
70.5
38.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
93.3
93.3
N.A.
100
100
N.A.
6.6
73.3
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
100
N.A.
100
100
N.A.
13.3
86.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
70
0
0
0
0
10
0
0
10
60
0
% D
% Glu:
0
60
60
0
0
10
0
0
40
10
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
10
0
0
0
0
0
40
0
10
% F
% Gly:
0
0
0
0
0
0
0
10
0
20
0
0
10
0
0
% G
% His:
0
0
0
10
0
0
0
0
20
0
0
0
10
0
10
% H
% Ile:
10
0
0
0
0
0
60
0
0
0
10
10
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
70
0
10
70
0
0
0
10
10
0
0
60
20
10
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
0
0
0
0
10
0
10
10
% P
% Gln:
0
0
0
0
10
10
0
0
10
60
0
0
0
0
0
% Q
% Arg:
0
10
0
10
0
70
10
0
20
0
10
0
0
0
0
% R
% Ser:
10
0
0
0
10
10
0
0
0
0
10
10
0
10
0
% S
% Thr:
0
0
0
0
10
0
10
60
0
0
60
0
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _