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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFBR2
All Species:
40.3
Human Site:
S409
Identified Species:
80.61
UniProt:
P37173
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37173
NP_001020018.1
567
64568
S409
L
R
L
D
P
T
L
S
V
D
D
L
A
N
S
Chimpanzee
Pan troglodytes
XP_001166587
603
68631
S445
L
R
L
D
P
T
L
S
V
D
D
L
A
N
S
Rhesus Macaque
Macaca mulatta
XP_001095987
567
64487
S409
L
R
L
D
P
T
L
S
V
D
D
L
A
N
S
Dog
Lupus familis
XP_534237
569
64614
S411
L
R
L
D
P
T
L
S
V
D
D
L
A
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62312
592
67103
S434
L
R
L
D
P
T
L
S
V
D
D
L
A
N
S
Rat
Rattus norvegicus
P38438
567
64223
S409
L
R
L
D
P
T
L
S
V
D
D
L
A
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508269
597
68110
S439
L
R
L
D
P
T
L
S
V
D
D
L
A
N
S
Chicken
Gallus gallus
Q90999
557
63290
S399
L
R
L
D
P
S
L
S
V
D
D
L
A
N
S
Frog
Xenopus laevis
P27041
511
57917
T354
P
G
K
P
P
G
D
T
H
G
Q
V
G
T
R
Zebra Danio
Brachydanio rerio
NP_878275
556
63419
S395
L
R
L
D
N
S
L
S
V
D
E
L
A
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P50488
744
84391
D468
L
A
R
I
Y
S
Y
D
I
E
Q
S
D
L
L
Sea Urchin
Strong. purpuratus
XP_001184520
615
68501
S434
I
R
L
D
P
Q
S
S
T
D
H
L
A
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
98.9
89.4
N.A.
88.1
91.5
N.A.
74.5
74.9
34
66.8
N.A.
N.A.
N.A.
25.1
32.3
Protein Similarity:
100
94
99.6
93.5
N.A.
92.9
96.3
N.A.
82
85.1
51.6
79.8
N.A.
N.A.
N.A.
42.2
49.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
6.6
80
N.A.
N.A.
N.A.
6.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
20
93.3
N.A.
N.A.
N.A.
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
84
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
84
0
0
9
9
0
84
67
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
9
0
0
0
9
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
9
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
84
0
84
0
0
0
75
0
0
0
0
84
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
84
0
% N
% Pro:
9
0
0
9
84
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
17
0
0
0
0
% Q
% Arg:
0
84
9
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
0
0
25
9
84
0
0
0
9
0
0
84
% S
% Thr:
0
0
0
0
0
59
0
9
9
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
75
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _