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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFBR2
All Species:
35.76
Human Site:
Y470
Identified Species:
71.52
UniProt:
P37173
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37173
NP_001020018.1
567
64568
Y470
A
V
G
E
V
K
D
Y
E
P
P
F
G
S
K
Chimpanzee
Pan troglodytes
XP_001166587
603
68631
Y506
A
V
G
E
V
K
D
Y
E
P
P
F
G
S
K
Rhesus Macaque
Macaca mulatta
XP_001095987
567
64487
Y470
A
V
G
E
V
K
D
Y
E
P
P
F
G
S
K
Dog
Lupus familis
XP_534237
569
64614
Y472
A
V
G
E
V
K
D
Y
E
P
P
F
G
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q62312
592
67103
Y495
A
V
G
E
V
K
D
Y
E
P
P
F
G
S
K
Rat
Rattus norvegicus
P38438
567
64223
Y470
A
V
G
E
V
K
D
Y
E
P
P
F
G
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508269
597
68110
Y500
G
I
G
E
V
K
D
Y
E
P
P
F
G
S
K
Chicken
Gallus gallus
Q90999
557
63290
Y460
G
V
G
E
V
K
E
Y
E
P
P
F
G
S
K
Frog
Xenopus laevis
P27041
511
57917
E415
E
Y
L
L
P
F
E
E
E
I
G
Q
H
P
S
Zebra Danio
Brachydanio rerio
NP_878275
556
63419
Y456
A
I
G
E
V
K
D
Y
E
P
P
F
G
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P50488
744
84391
N529
H
Q
T
D
E
P
P
N
Y
Q
M
P
F
Q
V
Sea Urchin
Strong. purpuratus
XP_001184520
615
68501
F495
L
L
K
G
L
L
I
F
V
T
I
F
T
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
98.9
89.4
N.A.
88.1
91.5
N.A.
74.5
74.9
34
66.8
N.A.
N.A.
N.A.
25.1
32.3
Protein Similarity:
100
94
99.6
93.5
N.A.
92.9
96.3
N.A.
82
85.1
51.6
79.8
N.A.
N.A.
N.A.
42.2
49.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
6.6
93.3
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
13.3
100
N.A.
N.A.
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
67
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
75
9
0
17
9
84
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
9
0
0
0
84
9
0
0
% F
% Gly:
17
0
75
9
0
0
0
0
0
0
9
0
75
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
17
0
0
0
0
9
0
0
9
9
0
0
0
0
% I
% Lys:
0
0
9
0
0
75
0
0
0
0
0
0
0
0
75
% K
% Leu:
9
9
9
9
9
9
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
9
9
0
0
75
75
9
0
9
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
9
0
9
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
9
% S
% Thr:
0
0
9
0
0
0
0
0
0
9
0
0
9
0
0
% T
% Val:
0
59
0
0
75
0
0
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
75
9
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _