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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPARG
All Species:
19.09
Human Site:
Y250
Identified Species:
52.5
UniProt:
P37231
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37231
NP_005028.4
505
57620
Y250
A
K
H
L
Y
D
S
Y
I
K
S
F
P
L
T
Chimpanzee
Pan troglodytes
XP_001153669
505
57634
Y250
A
K
H
L
Y
D
S
Y
I
K
S
F
P
L
T
Rhesus Macaque
Macaca mulatta
O18924
505
57572
Y250
A
K
H
L
Y
D
S
Y
I
K
S
F
P
L
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P37238
505
57580
Y250
A
K
H
L
Y
D
S
Y
I
K
S
F
P
L
T
Rat
Rattus norvegicus
O88275
505
57549
Y250
A
K
H
L
Y
D
S
Y
I
K
S
F
P
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P22448
455
50690
A232
W
D
K
F
S
E
L
A
T
K
C
I
I
K
I
Frog
Xenopus laevis
P37234
477
54037
H244
G
H
P
D
G
Q
S
H
R
Q
N
S
R
G
Y
Zebra Danio
Brachydanio rerio
Q90271
444
49906
K221
K
F
S
E
L
S
T
K
C
I
I
K
T
V
E
Tiger Blowfish
Takifugu rubipres
Q9W5Z3
447
49514
S224
W
D
K
F
S
E
L
S
T
K
C
I
I
K
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.2
N.A.
N.A.
96
95.8
N.A.
N.A.
21.1
70.6
23.3
21.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.8
N.A.
N.A.
98
97.8
N.A.
N.A.
38
79.8
38
37.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
6.6
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
13.3
26.6
13.3
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
56
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
23
0
0
0
0
% C
% Asp:
0
23
0
12
0
56
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
12
0
23
0
0
0
0
0
0
0
0
12
% E
% Phe:
0
12
0
23
0
0
0
0
0
0
0
56
0
0
0
% F
% Gly:
12
0
0
0
12
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
12
56
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
56
12
12
23
23
0
12
% I
% Lys:
12
56
23
0
0
0
0
12
0
78
0
12
0
23
0
% K
% Leu:
0
0
0
56
12
0
23
0
0
0
0
0
0
56
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
0
56
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% R
% Ser:
0
0
12
0
23
12
67
12
0
0
56
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
0
23
0
0
0
12
0
67
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
56
0
0
56
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _