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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPCAL1
All Species:
42.12
Human Site:
Y108
Identified Species:
71.28
UniProt:
P37235
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37235
NP_002140.2
193
22313
Y108
L
K
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Chimpanzee
Pan troglodytes
XP_001155509
344
38260
Y259
L
M
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Rhesus Macaque
Macaca mulatta
XP_001098851
408
45214
Y323
L
M
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Dog
Lupus familis
XP_852217
329
37131
Y244
L
K
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGZ1
191
22197
E106
Q
K
L
N
W
A
F
E
M
Y
D
L
D
G
D
Rat
Rattus norvegicus
P62749
193
22320
Y108
L
K
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P42324
193
22251
Y108
L
K
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Frog
Xenopus laevis
Q6DCM9
193
22267
Y108
L
K
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Zebra Danio
Brachydanio rerio
A9JTH1
193
22206
Y108
L
K
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42325
190
21875
S106
Q
K
L
K
W
A
F
S
M
Y
D
L
D
G
N
Honey Bee
Apis mellifera
XP_392256
192
21952
Y108
L
K
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Nematode Worm
Caenorhab. elegans
P36608
191
22003
K106
E
K
L
H
W
A
F
K
L
Y
D
L
D
Q
D
Sea Urchin
Strong. purpuratus
XP_783112
194
22350
Y108
L
K
W
A
F
S
M
Y
D
L
D
G
N
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06389
190
21992
E106
E
K
L
S
W
A
F
E
L
Y
D
L
N
H
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.9
44.3
58.3
N.A.
66.3
98.4
N.A.
N.A.
98.4
96.8
89.6
N.A.
87.5
87
58
87.1
Protein Similarity:
100
54.3
45.8
58.6
N.A.
81.8
99.4
N.A.
N.A.
99.4
98.9
97.4
N.A.
92.2
93.7
73.5
92.2
P-Site Identity:
100
93.3
93.3
100
N.A.
20
100
N.A.
N.A.
100
100
100
N.A.
20
100
13.3
100
P-Site Similarity:
100
93.3
93.3
100
N.A.
40
100
N.A.
N.A.
100
100
100
N.A.
40
100
33.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
48.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
66.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
72
0
29
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
72
0
100
0
22
0
22
% D
% Glu:
15
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
72
0
29
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
72
0
86
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
86
0
8
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
72
0
29
0
0
0
0
0
15
72
0
29
0
0
0
% L
% Met:
0
15
0
0
0
0
72
0
15
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
79
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
72
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
72
0
29
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
72
0
29
0
0
0
0
72
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _