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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FDFT1 All Species: 28.18
Human Site: S378 Identified Species: 47.69
UniProt: P37268 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P37268 NP_004453.3 417 48115 S378 L P N C Q L I S R S H Y S P I
Chimpanzee Pan troglodytes XP_001140917 410 47295 S371 L P N C Q L I S R S H Y S P I
Rhesus Macaque Macaca mulatta XP_001086419 417 48141 S378 L P N C Q L I S R S H Y S P I
Dog Lupus familis XP_534557 417 48183 S378 L P N C Q L I S R S H Y S P I
Cat Felis silvestris
Mouse Mus musculus P53798 416 48108 S378 L P N C Q L I S R S H Y S P I
Rat Rattus norvegicus Q02769 416 48088 S378 L P N C Q L I S R S H Y S P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034383 418 47994 S379 L P S G P M A S R H H Y S P I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700647 418 47159 S378 V H E G C V S S R A H H H I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790906 411 46993 G370 I T T V T S L G E D T M I T G
Poplar Tree Populus trichocarpa XP_002305455 413 47272 K375 R E S G A L N K R K S Y I I R
Maize Zea mays NP_001130502 403 46159 C363 V N S I K Q T C K S S G L V K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P53799 410 47123 R370 E A V Q K L C R D A G V L Q N
Baker's Yeast Sacchar. cerevisiae P29704 444 51701 L385 E E M Y Q D K L P P N V K P N
Red Bread Mold Neurospora crassa Q7S4Z6 481 54924 Q388 I E S I F P T Q D P K K I A L
Conservation
Percent
Protein Identity: 100 98.3 99.5 93.5 N.A. 88 85.8 N.A. N.A. 76 N.A. 67.4 N.A. N.A. N.A. N.A. 59.2
Protein Similarity: 100 98.3 99.7 97.1 N.A. 95.1 94.7 N.A. N.A. 89.7 N.A. 81 N.A. N.A. N.A. N.A. 77.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 60 N.A. 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 73.3 N.A. 46.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 42.6 42.4 N.A. 40.2 41.2 37.6
Protein Similarity: 59.7 60.1 N.A. 59.9 59 53.8
P-Site Identity: 20 6.6 N.A. 6.6 13.3 0
P-Site Similarity: 26.6 33.3 N.A. 20 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 8 0 0 15 0 0 0 8 0 % A
% Cys: 0 0 0 43 8 0 8 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 15 8 0 0 0 0 0 % D
% Glu: 15 22 8 0 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 22 0 0 0 8 0 0 8 8 0 0 8 % G
% His: 0 8 0 0 0 0 0 0 0 8 58 8 8 0 0 % H
% Ile: 15 0 0 15 0 0 43 0 0 0 0 0 22 15 50 % I
% Lys: 0 0 0 0 15 0 8 8 8 8 8 8 8 0 8 % K
% Leu: 50 0 0 0 0 58 8 8 0 0 0 0 15 0 8 % L
% Met: 0 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 43 0 0 0 8 0 0 0 8 0 0 0 15 % N
% Pro: 0 50 0 0 8 8 0 0 8 15 0 0 0 58 0 % P
% Gln: 0 0 0 8 50 8 0 8 0 0 0 0 0 8 0 % Q
% Arg: 8 0 0 0 0 0 0 8 65 0 0 0 0 0 8 % R
% Ser: 0 0 29 0 0 8 8 58 0 50 15 0 50 0 8 % S
% Thr: 0 8 8 0 8 0 15 0 0 0 8 0 0 8 0 % T
% Val: 15 0 8 8 0 8 0 0 0 0 0 15 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 58 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _