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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDFT1
All Species:
26.67
Human Site:
Y346
Identified Species:
45.13
UniProt:
P37268
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37268
NP_004453.3
417
48115
Y346
Y
Q
Y
M
E
E
I
Y
H
R
I
P
D
S
D
Chimpanzee
Pan troglodytes
XP_001140917
410
47295
Y339
Y
Q
Y
M
E
E
I
Y
H
R
I
P
D
S
D
Rhesus Macaque
Macaca mulatta
XP_001086419
417
48141
Y346
Y
Q
Y
M
E
E
I
Y
H
R
I
P
D
S
D
Dog
Lupus familis
XP_534557
417
48183
Y346
Y
Q
Y
M
E
E
I
Y
H
R
I
P
S
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P53798
416
48108
Y346
Y
Q
Y
I
E
E
I
Y
H
R
I
P
N
S
D
Rat
Rattus norvegicus
Q02769
416
48088
Y346
Y
Q
Y
I
E
E
I
Y
H
R
V
P
N
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034383
418
47994
Y347
Y
Q
Y
V
E
E
I
Y
Q
K
I
P
S
T
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700647
418
47159
L346
T
Q
Y
S
H
E
I
L
Q
K
V
S
I
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790906
411
46993
L338
F
Q
S
L
R
R
I
L
Y
K
Y
A
Q
E
I
Poplar Tree
Populus trichocarpa
XP_002305455
413
47272
K343
F
D
F
S
C
M
L
K
F
K
V
D
N
S
D
Maize
Zea mays
NP_001130502
403
46159
F331
M
S
D
V
Y
T
A
F
Y
E
F
S
S
L
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53799
410
47123
Y338
A
D
V
Y
G
A
F
Y
D
F
S
C
M
L
K
Baker's Yeast
Sacchar. cerevisiae
P29704
444
51701
K353
D
Y
Y
L
R
D
I
K
S
K
L
A
V
Q
D
Red Bread Mold
Neurospora crassa
Q7S4Z6
481
54924
I356
F
R
R
Y
A
R
R
I
H
K
K
N
D
P
R
Conservation
Percent
Protein Identity:
100
98.3
99.5
93.5
N.A.
88
85.8
N.A.
N.A.
76
N.A.
67.4
N.A.
N.A.
N.A.
N.A.
59.2
Protein Similarity:
100
98.3
99.7
97.1
N.A.
95.1
94.7
N.A.
N.A.
89.7
N.A.
81
N.A.
N.A.
N.A.
N.A.
77.4
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
N.A.
66.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
86.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
42.6
42.4
N.A.
40.2
41.2
37.6
Protein Similarity:
59.7
60.1
N.A.
59.9
59
53.8
P-Site Identity:
13.3
0
N.A.
6.6
20
13.3
P-Site Similarity:
53.3
20
N.A.
6.6
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
8
0
0
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
15
8
0
0
8
0
0
8
0
0
8
29
0
72
% D
% Glu:
0
0
0
0
50
58
0
0
0
8
0
0
0
8
0
% E
% Phe:
22
0
8
0
0
0
8
8
8
8
8
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
50
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
72
8
0
0
43
0
8
0
15
% I
% Lys:
0
0
0
0
0
0
0
15
0
43
8
0
0
0
8
% K
% Leu:
0
0
0
15
0
0
8
15
0
0
8
0
0
15
0
% L
% Met:
8
0
0
29
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
22
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
50
0
8
0
% P
% Gln:
0
65
0
0
0
0
0
0
15
0
0
0
8
8
0
% Q
% Arg:
0
8
8
0
15
15
8
0
0
43
0
0
0
0
8
% R
% Ser:
0
8
8
15
0
0
0
0
8
0
8
15
22
58
0
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
8
15
0
0
0
0
0
0
22
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
8
65
15
8
0
0
58
15
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _