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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGA
All Species:
27.58
Human Site:
S130
Identified Species:
43.33
UniProt:
P37287
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37287
NP_002632.1
484
54127
S130
T
I
I
H
S
H
S
S
F
S
A
M
A
H
D
Chimpanzee
Pan troglodytes
XP_520945
484
54135
S130
T
I
I
H
S
H
S
S
F
S
A
M
A
H
D
Rhesus Macaque
Macaca mulatta
XP_001100879
484
54016
S130
T
I
I
H
S
H
S
S
F
S
A
M
A
H
D
Dog
Lupus familis
XP_548868
485
54195
S130
T
I
I
H
S
H
S
S
F
S
A
M
A
H
D
Cat
Felis silvestris
Mouse
Mus musculus
Q64323
485
54450
S130
T
I
I
H
S
H
S
S
F
S
A
M
A
H
D
Rat
Rattus norvegicus
NP_001102286
252
28487
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515555
485
54365
S130
T
I
I
H
S
H
S
S
F
S
A
M
A
H
D
Chicken
Gallus gallus
NP_001025979
477
53438
H128
L
R
T
V
F
T
D
H
S
L
F
G
F
A
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001119918
487
54140
S134
T
I
V
H
A
H
S
S
F
S
A
M
A
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397085
442
50212
F124
L
M
G
L
K
T
I
F
T
D
H
S
L
F
G
Nematode Worm
Caenorhab. elegans
NP_495840
444
49466
V125
G
L
M
G
L
R
T
V
F
T
D
H
S
L
F
Sea Urchin
Strong. purpuratus
XP_789293
461
51539
H124
L
K
T
V
F
T
D
H
S
L
F
G
F
A
D
Poplar Tree
Populus trichocarpa
XP_002323038
433
49503
Y115
M
H
A
R
T
M
G
Y
K
V
V
F
T
D
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566874
447
50406
F125
T
M
G
Y
K
V
V
F
T
D
H
S
L
Y
G
Baker's Yeast
Sacchar. cerevisiae
P32363
452
51224
G128
F
T
D
H
S
L
Y
G
F
N
N
L
T
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.6
92.9
N.A.
87.6
45.4
N.A.
88.4
83.4
N.A.
73.3
N.A.
N.A.
52.8
49.5
55.9
Protein Similarity:
100
100
98.3
95.8
N.A.
93.4
49.7
N.A.
93.1
90
N.A.
83.7
N.A.
N.A.
67.9
65
71
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
6.6
N.A.
86.6
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
100
6.6
N.A.
100
N.A.
N.A.
6.6
40
6.6
Percent
Protein Identity:
46.9
N.A.
N.A.
48.9
42.3
N.A.
Protein Similarity:
63.8
N.A.
N.A.
66.7
61.3
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
0
0
0
0
0
47
0
47
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
14
0
0
14
7
0
0
7
60
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
14
0
0
14
60
0
14
7
14
7
7
% F
% Gly:
7
0
14
7
0
0
7
7
0
0
0
14
0
0
14
% G
% His:
0
7
0
54
0
47
0
14
0
0
14
7
0
47
7
% H
% Ile:
0
47
40
0
0
0
7
0
0
0
0
0
0
0
7
% I
% Lys:
0
7
0
0
14
0
0
0
7
0
0
0
0
0
0
% K
% Leu:
20
7
0
7
7
7
0
0
0
14
0
7
14
7
0
% L
% Met:
7
14
7
0
0
7
0
0
0
0
0
47
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
7
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
47
0
47
47
14
47
0
14
7
7
0
% S
% Thr:
54
7
14
0
7
20
7
0
14
7
0
0
14
0
0
% T
% Val:
0
0
7
14
0
7
7
7
0
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
7
7
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _