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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGA
All Species:
32.73
Human Site:
S354
Identified Species:
51.43
UniProt:
P37287
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37287
NP_002632.1
484
54127
S354
L
C
E
P
S
V
K
S
L
C
E
G
L
E
K
Chimpanzee
Pan troglodytes
XP_520945
484
54135
S354
L
C
E
P
S
V
K
S
L
C
E
G
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001100879
484
54016
S354
L
C
E
P
S
V
K
S
L
C
E
G
L
E
K
Dog
Lupus familis
XP_548868
485
54195
S355
L
C
E
P
S
V
K
S
L
C
K
G
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64323
485
54450
S355
L
C
E
P
S
V
K
S
L
C
D
G
L
E
K
Rat
Rattus norvegicus
NP_001102286
252
28487
K129
S
L
C
E
G
L
E
K
A
I
F
Q
V
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515555
485
54365
S355
L
C
E
P
S
V
K
S
L
C
D
G
L
E
K
Chicken
Gallus gallus
NP_001025979
477
53438
S329
L
C
E
P
S
V
K
S
L
C
D
G
L
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001119918
487
54140
S359
L
C
G
P
S
V
C
S
L
C
D
G
L
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397085
442
50212
I319
E
V
L
P
P
D
L
I
Y
L
V
E
P
T
V
Nematode Worm
Caenorhab. elegans
NP_495840
444
49466
E321
P
E
V
L
P
I
G
E
F
I
S
L
E
E
P
Sea Urchin
Strong. purpuratus
XP_789293
461
51539
G325
L
V
E
P
S
V
K
G
I
L
S
G
L
E
E
Poplar Tree
Populus trichocarpa
XP_002323038
433
49503
I310
G
G
V
P
E
A
C
I
M
R
E
D
M
I
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566874
447
50406
E324
D
D
M
V
V
L
A
E
P
D
P
D
D
M
V
Baker's Yeast
Sacchar. cerevisiae
P32363
452
51224
T328
M
T
V
Y
A
E
Q
T
S
V
S
D
L
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.6
92.9
N.A.
87.6
45.4
N.A.
88.4
83.4
N.A.
73.3
N.A.
N.A.
52.8
49.5
55.9
Protein Similarity:
100
100
98.3
95.8
N.A.
93.4
49.7
N.A.
93.1
90
N.A.
83.7
N.A.
N.A.
67.9
65
71
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
93.3
93.3
N.A.
73.3
N.A.
N.A.
6.6
6.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
100
N.A.
80
N.A.
N.A.
6.6
13.3
73.3
Percent
Protein Identity:
46.9
N.A.
N.A.
48.9
42.3
N.A.
Protein Similarity:
63.8
N.A.
N.A.
66.7
61.3
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
6.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
7
0
7
0
0
0
0
0
0
% A
% Cys:
0
54
7
0
0
0
14
0
0
54
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
7
0
0
0
7
27
20
7
0
0
% D
% Glu:
7
7
54
7
7
7
7
14
0
0
27
7
7
67
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% F
% Gly:
7
7
7
0
7
0
7
7
0
0
0
60
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
14
7
14
0
0
0
7
0
% I
% Lys:
0
0
0
0
0
0
54
7
0
0
7
0
0
7
47
% K
% Leu:
60
7
7
7
0
14
7
0
54
14
0
7
67
0
0
% L
% Met:
7
0
7
0
0
0
0
0
7
0
0
0
7
7
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
74
14
0
0
0
7
0
7
0
7
0
7
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
7
0
0
0
60
0
0
54
7
0
20
0
0
0
7
% S
% Thr:
0
7
0
0
0
0
0
7
0
0
0
0
0
7
7
% T
% Val:
0
14
20
7
7
60
0
0
0
7
7
0
7
7
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _