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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGA
All Species:
22.12
Human Site:
T465
Identified Species:
34.76
UniProt:
P37287
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37287
NP_002632.1
484
54127
T465
T
G
P
R
G
A
W
T
N
N
Y
S
H
S
K
Chimpanzee
Pan troglodytes
XP_520945
484
54135
T465
T
G
P
R
G
A
W
T
N
N
Y
S
H
S
K
Rhesus Macaque
Macaca mulatta
XP_001100879
484
54016
T465
T
G
P
Q
G
A
W
T
N
N
Y
S
H
S
K
Dog
Lupus familis
XP_548868
485
54195
T466
T
G
P
K
G
A
W
T
H
Q
Y
P
Y
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64323
485
54450
T466
T
G
P
R
R
A
W
T
H
Q
W
P
R
D
K
Rat
Rattus norvegicus
NP_001102286
252
28487
H234
G
P
R
R
A
W
T
H
Q
W
P
R
D
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515555
485
54365
T466
T
G
P
N
G
A
W
T
R
Q
Y
S
F
S
K
Chicken
Gallus gallus
NP_001025979
477
53438
T440
T
G
P
N
G
A
W
T
K
Q
Y
F
L
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001119918
487
54140
P465
V
A
V
D
A
S
G
P
H
S
R
L
K
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397085
442
50212
A424
P
R
K
Y
I
D
V
A
K
E
Y
T
E
T
D
Nematode Worm
Caenorhab. elegans
NP_495840
444
49466
R426
L
D
L
F
D
S
P
R
K
N
G
T
N
D
K
Sea Urchin
Strong. purpuratus
XP_789293
461
51539
K435
P
E
A
Q
S
L
T
K
G
T
E
C
P
S
A
Poplar Tree
Populus trichocarpa
XP_002323038
433
49503
I415
C
G
S
W
A
G
K
I
F
C
F
V
M
I
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566874
447
50406
C429
I
E
E
A
P
D
I
C
L
C
H
H
R
G
V
Baker's Yeast
Sacchar. cerevisiae
P32363
452
51224
A434
P
R
D
E
I
D
L
A
P
K
W
P
K
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.6
92.9
N.A.
87.6
45.4
N.A.
88.4
83.4
N.A.
73.3
N.A.
N.A.
52.8
49.5
55.9
Protein Similarity:
100
100
98.3
95.8
N.A.
93.4
49.7
N.A.
93.1
90
N.A.
83.7
N.A.
N.A.
67.9
65
71
P-Site Identity:
100
100
93.3
66.6
N.A.
53.3
13.3
N.A.
73.3
60
N.A.
0
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
13.3
N.A.
73.3
60
N.A.
26.6
N.A.
N.A.
20
33.3
13.3
Percent
Protein Identity:
46.9
N.A.
N.A.
48.9
42.3
N.A.
Protein Similarity:
63.8
N.A.
N.A.
66.7
61.3
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
7
20
47
0
14
0
0
0
0
0
0
7
% A
% Cys:
7
0
0
0
0
0
0
7
0
14
0
7
0
0
0
% C
% Asp:
0
7
7
7
7
20
0
0
0
0
0
0
7
14
7
% D
% Glu:
0
14
7
7
0
0
0
0
0
7
7
0
7
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
7
0
7
7
7
0
0
% F
% Gly:
7
54
0
0
40
7
7
0
7
0
7
0
0
14
0
% G
% His:
0
0
0
0
0
0
0
7
20
0
7
7
20
0
0
% H
% Ile:
7
0
0
0
14
0
7
7
0
0
0
0
0
7
7
% I
% Lys:
0
0
7
7
0
0
7
7
20
7
0
0
14
14
60
% K
% Leu:
7
0
7
0
0
7
7
0
7
0
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
14
0
0
0
0
20
27
0
0
7
0
0
% N
% Pro:
20
7
47
0
7
0
7
7
7
0
7
20
7
0
0
% P
% Gln:
0
0
0
14
0
0
0
0
7
27
0
0
0
7
7
% Q
% Arg:
0
14
7
27
7
0
0
7
7
0
7
7
14
0
0
% R
% Ser:
0
0
7
0
7
14
0
0
0
7
0
27
0
40
0
% S
% Thr:
47
0
0
0
0
0
14
47
0
7
0
14
0
7
7
% T
% Val:
7
0
7
0
0
0
7
0
0
0
0
7
0
0
7
% V
% Trp:
0
0
0
7
0
7
47
0
0
7
14
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
47
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _