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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SNCA
All Species:
29.7
Human Site:
Y125
Identified Species:
72.59
UniProt:
P37840
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37840
NP_000336.1
140
14460
Y125
V
D
P
D
N
E
A
Y
E
M
P
S
E
E
G
Chimpanzee
Pan troglodytes
XP_001136812
134
14329
Y119
M
E
P
E
G
E
S
Y
E
D
P
P
Q
E
E
Rhesus Macaque
Macaca mulatta
XP_001095402
249
25993
Y234
V
D
P
D
N
E
A
Y
E
M
P
S
E
E
G
Dog
Lupus familis
XP_535656
140
14461
Y125
V
D
P
D
N
E
A
Y
E
M
P
S
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
O55042
140
14467
Y125
V
D
P
G
S
E
A
Y
E
M
P
S
E
E
G
Rat
Rattus norvegicus
P37377
140
14497
Y125
V
D
P
S
S
E
A
Y
E
M
P
S
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990004
143
15022
Y128
V
D
P
E
N
E
A
Y
E
M
P
P
E
E
E
Frog
Xenopus laevis
NP_001080623
141
14718
Y126
V
N
P
N
N
E
T
Y
E
M
P
P
E
E
E
Zebra Danio
Brachydanio rerio
NP_957263
127
13322
T112
L
M
D
P
E
G
Q
T
Y
D
D
N
Q
Q
E
Tiger Blowfish
Takifugu rubipres
NP_001029020
127
12563
P112
P
E
N
M
A
E
S
P
D
V
T
D
P
A
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
46.1
96.4
N.A.
95
95
N.A.
N.A.
86.7
84.4
52.1
57.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.5
51.8
97.1
N.A.
97.1
97.1
N.A.
N.A.
92.3
89.3
63.5
69.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
100
100
N.A.
86.6
86.6
N.A.
N.A.
80
66.6
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
26.6
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
60
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
10
30
0
0
0
0
10
20
10
10
0
0
0
% D
% Glu:
0
20
0
20
10
90
0
0
80
0
0
0
70
80
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
10
10
0
10
0
0
0
0
0
70
0
0
0
0
0
% M
% Asn:
0
10
10
10
50
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
0
80
10
0
0
0
10
0
0
80
30
10
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
20
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
20
0
20
0
0
0
0
50
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% T
% Val:
70
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _