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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V1A All Species: 48.18
Human Site: S145 Identified Species: 70.67
UniProt: P38606 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P38606 NP_001681.2 617 68304 S145 C K N L R V G S H I T G G D I
Chimpanzee Pan troglodytes XP_516655 617 68339 S145 C K N L R V G S H I T G G D I
Rhesus Macaque Macaca mulatta XP_001106889 617 68313 S145 C K N L R V G S H I T G G D I
Dog Lupus familis XP_545103 618 68384 S146 C K N L R V G S H I T G G D I
Cat Felis silvestris
Mouse Mus musculus P50516 617 68308 S145 S K N L R V G S H I T G G D I
Rat Rattus norvegicus NP_001101788 617 68247 S145 S K N L R V G S H I T G G D I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507849 617 68305 S145 C K N L R V G S H I T G G D I
Chicken Gallus gallus Q90647 617 68458 S145 S K N L R V G S H I T G G D I
Frog Xenopus laevis NP_001089571 617 68506 S145 S K S I R V G S H V T G G D I
Zebra Danio Brachydanio rerio XP_002666686 617 68360 S145 S K N L R V G S H I T G G D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27331 614 68283 S142 P L N V K V G S H I T G G D L
Honey Bee Apis mellifera XP_623495 616 68354 S144 P S N I K N G S H I T G G D L
Nematode Worm Caenorhab. elegans Q9XW92 606 66441 D140 G G H V T G G D I I G T V D E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49087 561 61933 S112 H V A L P P G S M G K I S Y I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23654 623 68794 D147 P N K F V E G D T I T G G D L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P11592 607 67103 I142 T M K V G D H I A G G D V W G
Conservation
Percent
Protein Identity: 100 99.5 99.8 98.5 N.A. 98 97.7 N.A. 96.2 95.3 93.1 93.1 N.A. 83.3 83.1 79.9 N.A.
Protein Similarity: 100 99.6 100 99.6 N.A. 99.3 99.1 N.A. 98.8 98 97.5 96.9 N.A. 91.9 93 89.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 93.3 73.3 93.3 N.A. 66.6 60 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 93.3 93.3 93.3 N.A. 86.6 80 33.3 N.A.
Percent
Protein Identity: N.A. 63.5 N.A. 68.5 N.A. 63.5
Protein Similarity: N.A. 76.5 N.A. 80.7 N.A. 78.9
P-Site Identity: N.A. 26.6 N.A. 40 N.A. 0
P-Site Similarity: N.A. 26.6 N.A. 46.6 N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % A
% Cys: 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 13 0 0 0 7 0 88 0 % D
% Glu: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 7 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 7 0 0 7 7 94 0 0 13 13 82 82 0 7 % G
% His: 7 0 7 0 0 0 7 0 75 0 0 0 0 0 0 % H
% Ile: 0 0 0 13 0 0 0 7 7 82 0 7 0 0 69 % I
% Lys: 0 63 13 0 13 0 0 0 0 0 7 0 0 0 0 % K
% Leu: 0 7 0 63 0 0 0 0 0 0 0 0 0 0 19 % L
% Met: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 7 69 0 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 63 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 32 7 7 0 0 0 0 82 0 0 0 0 7 0 0 % S
% Thr: 7 0 0 0 7 0 0 0 7 0 82 7 0 0 0 % T
% Val: 0 7 0 19 7 69 0 0 0 7 0 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _