Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V1A All Species: 22.12
Human Site: T17 Identified Species: 32.44
UniProt: P38606 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P38606 NP_001681.2 617 68304 T17 L D E D K E S T F G Y V H G V
Chimpanzee Pan troglodytes XP_516655 617 68339 T17 L D E D K E S T F G Y V H G V
Rhesus Macaque Macaca mulatta XP_001106889 617 68313 T17 L D E D K E S T F G Y V H G V
Dog Lupus familis XP_545103 618 68384 T18 L D E D K E S T F G Y V H G V
Cat Felis silvestris
Mouse Mus musculus P50516 617 68308 T17 R D E D K E S T F G Y V H G V
Rat Rattus norvegicus NP_001101788 617 68247 T17 R D E D K E S T F G Y V H G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507849 617 68305 A17 A D E D H E S A F G F V H G V
Chicken Gallus gallus Q90647 617 68458 F17 R D E D R E A F V G Y V Q G V
Frog Xenopus laevis NP_001089571 617 68506 Q17 R D E E R E S Q F G Y V H G V
Zebra Danio Brachydanio rerio XP_002666686 617 68360 Q17 R D E E R E G Q F G Y V H G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27331 614 68283 V19 R E S K Y G R V F A V S G P V
Honey Bee Apis mellifera XP_623495 616 68354 K17 S N E E R E T K F G Y V Y A V
Nematode Worm Caenorhab. elegans Q9XW92 606 66441 V17 V Y G V S G P V V T A E K M A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49087 561 61933
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23654 623 68794 E20 E D D E K E S E Y G Y V R K V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P11592 607 67103 K17 V D G I H T G K I Y S V S G P
Conservation
Percent
Protein Identity: 100 99.5 99.8 98.5 N.A. 98 97.7 N.A. 96.2 95.3 93.1 93.1 N.A. 83.3 83.1 79.9 N.A.
Protein Similarity: 100 99.6 100 99.6 N.A. 99.3 99.1 N.A. 98.8 98 97.5 96.9 N.A. 91.9 93 89.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 73.3 60 73.3 66.6 N.A. 13.3 46.6 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 80 73.3 86.6 80 N.A. 20 80 6.6 N.A.
Percent
Protein Identity: N.A. 63.5 N.A. 68.5 N.A. 63.5
Protein Similarity: N.A. 76.5 N.A. 80.7 N.A. 78.9
P-Site Identity: N.A. 0 N.A. 53.3 N.A. 20
P-Site Similarity: N.A. 0 N.A. 73.3 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 7 7 0 7 7 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 75 7 50 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 7 7 69 25 0 75 0 7 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 69 0 7 0 0 0 0 % F
% Gly: 0 0 13 0 0 13 13 0 0 75 0 0 7 69 0 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 0 57 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 44 0 0 13 0 0 0 0 7 7 0 % K
% Leu: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 7 % P
% Gln: 0 0 0 0 0 0 0 13 0 0 0 0 7 0 0 % Q
% Arg: 38 0 0 0 25 0 7 0 0 0 0 0 7 0 0 % R
% Ser: 7 0 7 0 7 0 57 0 0 0 7 7 7 0 0 % S
% Thr: 0 0 0 0 0 7 7 38 0 7 0 0 0 0 0 % T
% Val: 13 0 0 7 0 0 0 13 13 0 7 82 0 0 82 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 0 7 7 69 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _