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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1A
All Species:
48.18
Human Site:
T175
Identified Species:
70.67
UniProt:
P38606
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38606
NP_001681.2
617
68304
T175
L
P
P
R
N
R
G
T
V
T
Y
I
A
P
P
Chimpanzee
Pan troglodytes
XP_516655
617
68339
T175
L
P
P
R
N
R
G
T
V
T
Y
I
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001106889
617
68313
T175
L
P
P
R
N
R
G
T
V
T
Y
I
A
P
P
Dog
Lupus familis
XP_545103
618
68384
T176
L
P
P
R
N
R
G
T
V
T
Y
I
A
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P50516
617
68308
S175
L
P
P
R
N
R
G
S
V
T
Y
I
A
P
P
Rat
Rattus norvegicus
NP_001101788
617
68247
S175
L
P
P
R
S
R
G
S
V
T
Y
I
A
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507849
617
68305
T175
L
P
P
R
S
R
G
T
V
T
Y
L
A
P
A
Chicken
Gallus gallus
Q90647
617
68458
T175
L
P
P
R
N
R
G
T
V
T
Y
I
A
P
P
Frog
Xenopus laevis
NP_001089571
617
68506
T175
L
P
P
R
N
R
G
T
V
T
Y
V
A
P
P
Zebra Danio
Brachydanio rerio
XP_002666686
617
68360
T175
L
P
P
K
S
R
G
T
V
T
Y
V
A
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27331
614
68283
T172
V
N
P
R
A
K
G
T
V
R
Y
I
A
P
S
Honey Bee
Apis mellifera
XP_623495
616
68354
T174
L
P
P
K
S
K
G
T
V
T
Y
I
A
P
A
Nematode Worm
Caenorhab. elegans
Q9XW92
606
66441
P170
G
T
I
T
F
V
A
P
S
G
Q
Y
T
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49087
561
61933
K142
E
F
Q
G
I
K
K
K
F
T
M
L
Q
T
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23654
623
68794
K177
L
P
P
D
A
M
G
K
I
T
Y
I
A
P
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P11592
607
67103
I172
P
P
R
A
R
G
T
I
T
R
I
A
E
K
G
Conservation
Percent
Protein Identity:
100
99.5
99.8
98.5
N.A.
98
97.7
N.A.
96.2
95.3
93.1
93.1
N.A.
83.3
83.1
79.9
N.A.
Protein Similarity:
100
99.6
100
99.6
N.A.
99.3
99.1
N.A.
98.8
98
97.5
96.9
N.A.
91.9
93
89.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
80
100
93.3
80
N.A.
60
73.3
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
100
100
N.A.
73.3
93.3
0
N.A.
Percent
Protein Identity:
N.A.
63.5
N.A.
68.5
N.A.
63.5
Protein Similarity:
N.A.
76.5
N.A.
80.7
N.A.
78.9
P-Site Identity:
N.A.
6.6
N.A.
60
N.A.
6.6
P-Site Similarity:
N.A.
20
N.A.
66.6
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
13
0
7
0
0
0
0
7
82
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% E
% Phe:
0
7
0
0
7
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
7
0
0
7
0
7
82
0
0
7
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
7
0
0
7
7
0
7
63
0
0
0
% I
% Lys:
0
0
0
13
0
19
7
13
0
0
0
0
0
7
0
% K
% Leu:
75
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
7
0
0
44
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
82
82
0
0
0
0
7
0
0
0
0
0
82
57
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
7
0
7
0
0
% Q
% Arg:
0
0
7
63
7
63
0
0
0
13
0
0
0
0
0
% R
% Ser:
0
0
0
0
25
0
0
13
7
0
0
0
0
0
7
% S
% Thr:
0
7
0
7
0
0
7
63
7
82
0
0
7
7
0
% T
% Val:
7
0
0
0
0
7
0
0
75
0
0
13
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
82
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _