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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1A
All Species:
54.55
Human Site:
Y274
Identified Species:
80
UniProt:
P38606
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38606
NP_001681.2
617
68304
Y274
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Chimpanzee
Pan troglodytes
XP_516655
617
68339
Y274
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Rhesus Macaque
Macaca mulatta
XP_001106889
617
68313
Y274
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Dog
Lupus familis
XP_545103
618
68384
Y275
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Cat
Felis silvestris
Mouse
Mus musculus
P50516
617
68308
Y274
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Rat
Rattus norvegicus
NP_001101788
617
68247
Y274
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507849
617
68305
Y274
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Chicken
Gallus gallus
Q90647
617
68458
Y274
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Frog
Xenopus laevis
NP_001089571
617
68506
Y274
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Zebra Danio
Brachydanio rerio
XP_002666686
617
68360
Y274
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27331
614
68283
Y271
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Honey Bee
Apis mellifera
XP_623495
616
68354
Y273
S
N
S
D
V
I
I
Y
V
G
C
G
E
R
G
Nematode Worm
Caenorhab. elegans
Q9XW92
606
66441
G270
Y
V
G
C
G
E
R
G
N
E
M
S
E
V
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49087
561
61933
P239
P
Q
L
T
M
T
L
P
D
G
R
E
E
S
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23654
623
68794
V277
N
S
D
A
V
V
Y
V
G
C
G
E
R
G
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P11592
607
67103
Y270
S
N
S
D
V
I
V
Y
V
G
C
G
E
R
G
Conservation
Percent
Protein Identity:
100
99.5
99.8
98.5
N.A.
98
97.7
N.A.
96.2
95.3
93.1
93.1
N.A.
83.3
83.1
79.9
N.A.
Protein Similarity:
100
99.6
100
99.6
N.A.
99.3
99.1
N.A.
98.8
98
97.5
96.9
N.A.
91.9
93
89.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
100
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
100
6.6
N.A.
Percent
Protein Identity:
N.A.
63.5
N.A.
68.5
N.A.
63.5
Protein Similarity:
N.A.
76.5
N.A.
80.7
N.A.
78.9
P-Site Identity:
N.A.
13.3
N.A.
6.6
N.A.
93.3
P-Site Similarity:
N.A.
26.6
N.A.
26.6
N.A.
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
7
82
0
0
0
0
% C
% Asp:
0
0
7
82
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
7
0
13
94
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
7
0
0
7
7
88
7
82
0
7
82
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
82
75
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
82
0
0
0
0
0
0
7
0
0
0
0
0
7
% N
% Pro:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
7
0
7
82
0
% R
% Ser:
82
7
82
0
0
0
0
0
0
0
0
7
0
7
0
% S
% Thr:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
88
7
7
7
82
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _