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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4A3
All Species:
49.09
Human Site:
T303
Identified Species:
90
UniProt:
P38919
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38919
NP_055555.1
411
46871
T303
K
M
R
E
A
N
F
T
V
S
S
M
H
G
D
Chimpanzee
Pan troglodytes
XP_511724
543
61650
T435
K
M
R
E
A
N
F
T
V
S
S
M
H
G
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533130
411
46792
T303
K
M
R
E
A
N
F
T
V
S
S
M
H
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91VC3
411
46821
T303
K
M
R
E
A
N
F
T
V
S
S
M
H
G
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZM36
412
46797
T304
K
M
R
E
A
N
F
T
V
S
S
M
H
G
D
Frog
Xenopus laevis
Q5U526
415
46962
T307
K
M
R
E
A
N
F
T
V
S
S
M
H
G
D
Zebra Danio
Brachydanio rerio
Q7ZVA6
406
46449
T298
K
M
R
E
A
N
F
T
V
S
S
M
H
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649788
399
45626
T291
K
M
R
E
A
N
F
T
V
S
S
M
H
G
D
Honey Bee
Apis mellifera
XP_393356
403
46205
T295
K
M
R
E
A
N
F
T
V
C
S
M
H
G
D
Nematode Worm
Caenorhab. elegans
NP_490761
399
45564
T291
K
M
K
E
A
N
F
T
V
S
S
M
H
G
D
Sea Urchin
Strong. purpuratus
XP_785431
360
41204
A267
M
P
Q
K
E
R
E
A
I
M
K
E
F
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A52
408
45826
T300
K
M
R
S
H
N
F
T
V
S
S
M
H
G
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9P735
400
45389
T291
K
M
R
E
A
N
F
T
V
S
S
M
H
G
D
Conservation
Percent
Protein Identity:
100
75.5
N.A.
99.5
N.A.
99.2
N.A.
N.A.
N.A.
97.3
95.9
95.8
N.A.
85.4
86.1
84.4
82.2
Protein Similarity:
100
75.5
N.A.
99.5
N.A.
99.5
N.A.
N.A.
N.A.
98.5
96.8
96.8
N.A.
91.9
93.6
92.2
86.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
100
93.3
93.3
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
100
93.3
100
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
74.7
N.A.
78.3
Protein Similarity:
N.A.
N.A.
N.A.
87.8
N.A.
89.5
P-Site Identity:
N.A.
N.A.
N.A.
86.6
N.A.
100
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
N.A.
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
85
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
93
% D
% Glu:
0
0
0
85
8
0
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
93
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
93
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
93
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
93
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
93
0
0
0
0
0
0
0
8
0
93
0
0
0
% M
% Asn:
0
0
0
0
0
93
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
85
0
0
8
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
85
93
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _