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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4A3
All Species:
48.79
Human Site:
Y205
Identified Species:
89.44
UniProt:
P38919
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38919
NP_055555.1
411
46871
Y205
K
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Chimpanzee
Pan troglodytes
XP_511724
543
61650
Y337
K
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533130
411
46792
Y205
K
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91VC3
411
46821
Y205
K
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZM36
412
46797
Y206
K
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Frog
Xenopus laevis
Q5U526
415
46962
Y209
K
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Zebra Danio
Brachydanio rerio
Q7ZVA6
406
46449
Y200
K
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649788
399
45626
Y193
K
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Honey Bee
Apis mellifera
XP_393356
403
46205
Y197
K
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Nematode Worm
Caenorhab. elegans
NP_490761
399
45564
Y193
K
E
Q
L
Y
D
I
Y
R
Y
L
P
P
G
A
Sea Urchin
Strong. purpuratus
XP_785431
360
41204
I174
S
A
T
L
P
H
E
I
L
E
M
T
S
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A52
408
45826
Y202
K
D
Q
I
Y
D
V
Y
R
Y
L
P
P
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9P735
400
45389
Y193
R
E
Q
I
Y
D
V
Y
R
Y
L
P
P
A
T
Conservation
Percent
Protein Identity:
100
75.5
N.A.
99.5
N.A.
99.2
N.A.
N.A.
N.A.
97.3
95.9
95.8
N.A.
85.4
86.1
84.4
82.2
Protein Similarity:
100
75.5
N.A.
99.5
N.A.
99.5
N.A.
N.A.
N.A.
98.5
96.8
96.8
N.A.
91.9
93.6
92.2
86.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
100
100
73.3
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
100
100
86.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
74.7
N.A.
78.3
Protein Similarity:
N.A.
N.A.
N.A.
87.8
N.A.
89.5
P-Site Identity:
N.A.
N.A.
N.A.
80
N.A.
93.3
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
N.A.
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
77
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
93
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
85
0
0
0
0
8
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
85
0
0
8
8
0
0
0
0
0
0
0
% I
% Lys:
85
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
16
0
0
0
0
8
0
93
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
93
93
0
0
% P
% Gln:
0
0
93
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
77
% T
% Val:
0
0
0
0
0
0
85
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
93
0
0
93
0
93
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _