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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDKN1A All Species: 7.88
Human Site: S123 Identified Species: 24.76
UniProt: P38936 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P38936 NP_000380.1 164 18119 S123 S C T L V P R S G E Q A E G S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116881 164 18171 S123 S C T L V P R S G E Q P E E S
Dog Lupus familis XP_532125 208 21952 S167 T C T L L P H S P E R P E A S
Cat Felis silvestris
Mouse Mus musculus P39689 159 17767 V118 L S L S C T L V S E R P E D S
Rat Rattus norvegicus NP_542960 164 18300 A123 S C T L V S H A P E R P E D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989727 141 15801 A101 V G G A H R G A A Q Q S S E L
Frog Xenopus laevis NP_001087933 138 15622 S98 A T E R C N I S P S S K A F Q
Zebra Danio Brachydanio rerio XP_001923824 154 17589 C111 I P K T P E R C A A L P H E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.9 66.3 N.A. 77.4 75.6 N.A. N.A. 38.4 32.9 36.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 96.9 72.1 N.A. 82.3 82.3 N.A. N.A. 48.1 42.6 53 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 86.6 53.3 N.A. 20 53.3 N.A. N.A. 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 86.6 73.3 N.A. 26.6 66.6 N.A. N.A. 26.6 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 13 0 0 0 25 25 13 0 13 13 13 0 % A
% Cys: 0 50 0 0 25 0 0 13 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % D
% Glu: 0 0 13 0 0 13 0 0 0 63 0 0 63 38 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % F
% Gly: 0 13 13 0 0 0 13 0 25 0 0 0 0 13 0 % G
% His: 0 0 0 0 13 0 25 0 0 0 0 0 13 0 0 % H
% Ile: 13 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 13 0 0 0 0 0 0 0 0 13 0 0 0 % K
% Leu: 13 0 13 50 13 0 13 0 0 0 13 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 13 0 0 13 38 0 0 38 0 0 63 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 13 38 0 0 0 13 % Q
% Arg: 0 0 0 13 0 13 38 0 0 0 38 0 0 0 0 % R
% Ser: 38 13 0 13 0 13 0 50 13 13 13 13 13 0 63 % S
% Thr: 13 13 50 13 0 13 0 0 0 0 0 0 0 0 0 % T
% Val: 13 0 0 0 38 0 0 13 0 0 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _