KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDOST
All Species:
21.21
Human Site:
S221
Identified Species:
42.42
UniProt:
P39656
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39656
NP_005207.2
456
50801
S221
I
L
T
G
S
S
T
S
Y
S
F
F
P
D
K
Chimpanzee
Pan troglodytes
XP_001161661
456
50611
S221
I
L
T
G
S
S
T
S
Y
S
F
F
P
D
K
Rhesus Macaque
Macaca mulatta
XP_001097281
184
19986
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O54734
441
48995
S206
I
L
T
G
S
S
T
S
Y
S
F
F
P
D
K
Rat
Rattus norvegicus
Q641Y0
441
48877
S206
I
L
T
G
S
S
T
S
Y
S
F
F
P
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519134
372
41455
H151
K
P
I
T
Q
Y
P
H
A
V
G
K
N
T
L
Chicken
Gallus gallus
P48440
413
45894
H192
K
P
I
T
Q
Y
P
H
A
V
G
K
N
T
L
Frog
Xenopus laevis
Q6GNR9
438
48694
S205
T
G
S
S
T
S
Y
S
F
F
P
D
K
P
I
Zebra Danio
Brachydanio rerio
Q6NYS8
441
48515
S206
I
L
T
G
S
S
T
S
Y
S
Y
F
P
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24319
449
49962
S206
T
A
E
S
T
A
Y
S
Y
N
P
E
A
S
V
Honey Bee
Apis mellifera
XP_624433
423
46970
V202
I
K
E
Y
P
H
A
V
G
K
N
T
L
L
I
Nematode Worm
Caenorhab. elegans
P45971
445
48741
V207
Y
S
Y
D
P
K
A
V
R
A
T
N
P
S
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
39.9
N.A.
N.A.
92.3
91.8
N.A.
75.4
84.2
85.9
81.3
N.A.
58.3
59.6
51.5
N.A.
Protein Similarity:
100
99.5
40.1
N.A.
N.A.
94.3
94.3
N.A.
80
88.3
92.3
88.8
N.A.
73.6
73.9
67.5
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
100
100
N.A.
0
0
13.3
86.6
N.A.
13.3
6.6
6.6
N.A.
P-Site Similarity:
100
100
0
N.A.
N.A.
100
100
N.A.
0
0
33.3
100
N.A.
33.3
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
17
0
17
9
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
0
42
0
% D
% Glu:
0
0
17
0
0
0
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
9
34
42
0
0
0
% F
% Gly:
0
9
0
42
0
0
0
0
9
0
17
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
17
0
0
0
0
0
0
0
% H
% Ile:
50
0
17
0
0
0
0
0
0
0
0
0
0
0
25
% I
% Lys:
17
9
0
0
0
9
0
0
0
9
0
17
9
0
34
% K
% Leu:
0
42
0
0
0
0
0
0
0
0
0
0
9
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
9
9
17
0
0
% N
% Pro:
0
17
0
0
17
0
17
0
0
0
17
0
50
9
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% R
% Ser:
0
9
9
17
42
50
0
59
0
42
0
0
0
17
0
% S
% Thr:
17
0
42
17
17
0
42
0
0
0
9
9
0
17
0
% T
% Val:
0
0
0
0
0
0
0
17
0
17
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
9
0
17
17
0
50
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _