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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDOST All Species: 9.09
Human Site: S66 Identified Species: 18.18
UniProt: P39656 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P39656 NP_005207.2 456 50801 S66 T H S L F F R S L K D R G F E
Chimpanzee Pan troglodytes XP_001161661 456 50611 S66 T H S L F F R S L K D R G F E
Rhesus Macaque Macaca mulatta XP_001097281 184 19986
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O54734 441 48995 F61 D R G F E L T F K T A D D P S
Rat Rattus norvegicus Q641Y0 441 48877 F61 D R G F E L T F K T A D D P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519134 372 41455
Chicken Gallus gallus P48440 413 45894 G47 G L S L I K Y G E F L Y D N L
Frog Xenopus laevis Q6GNR9 438 48694 T60 G F D L S F K T A D D P S L S
Zebra Danio Brachydanio rerio Q6NYS8 441 48515 T60 A D R G F D L T F K T A D D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24319 449 49962 S61 T Y K L A D D S S L L L S K Y
Honey Bee Apis mellifera XP_624433 423 46970 Y57 Q L S K Y G E Y L Y Q H L I I
Nematode Worm Caenorhab. elegans P45971 445 48741 L60 R A A D D S Q L A L F K H G Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 39.9 N.A. N.A. 92.3 91.8 N.A. 75.4 84.2 85.9 81.3 N.A. 58.3 59.6 51.5 N.A.
Protein Similarity: 100 99.5 40.1 N.A. N.A. 94.3 94.3 N.A. 80 88.3 92.3 88.8 N.A. 73.6 73.9 67.5 N.A.
P-Site Identity: 100 100 0 N.A. N.A. 0 0 N.A. 0 13.3 20 13.3 N.A. 20 13.3 0 N.A.
P-Site Similarity: 100 100 0 N.A. N.A. 0 0 N.A. 0 13.3 33.3 20 N.A. 26.6 20 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 0 9 0 0 0 17 0 17 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 9 9 9 9 17 9 0 0 9 25 17 34 9 0 % D
% Glu: 0 0 0 0 17 0 9 0 9 0 0 0 0 0 17 % E
% Phe: 0 9 0 17 25 25 0 17 9 9 9 0 0 17 0 % F
% Gly: 17 0 17 9 0 9 0 9 0 0 0 0 17 9 0 % G
% His: 0 17 0 0 0 0 0 0 0 0 0 9 9 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 9 % I
% Lys: 0 0 9 9 0 9 9 0 17 25 0 9 0 9 0 % K
% Leu: 0 17 0 42 0 17 9 9 25 17 17 9 9 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 0 17 9 % P
% Gln: 9 0 0 0 0 0 9 0 0 0 9 0 0 0 9 % Q
% Arg: 9 17 9 0 0 0 17 0 0 0 0 17 0 0 0 % R
% Ser: 0 0 34 0 9 9 0 25 9 0 0 0 17 0 25 % S
% Thr: 25 0 0 0 0 0 17 17 0 17 9 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 9 0 9 9 0 9 0 9 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _