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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX1 All Species: 21.21
Human Site: S1063 Identified Species: 38.89
UniProt: P39880 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P39880 NP_853530.2 1505 164273 S1063 A P E S P M S S S E S V K S L
Chimpanzee Pan troglodytes XP_527845 1515 165612 S1074 A P E S P M S S S E S V K S L
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 S1340 A P E S P M S S S E S V K S L
Dog Lupus familis XP_546939 1411 154543 P1004 E S D P T R P P S R P P D P S
Cat Felis silvestris
Mouse Mus musculus P53564 1515 165577 S1058 A P E S P M S S S E S V K S L
Rat Rattus norvegicus P53565 862 92341 V462 A L S I Q E L V A M S P E L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 P1054 P E K S S Q E P L G L N L E S
Chicken Gallus gallus XP_425393 1673 183755 S1202 A P E S P M S S S E S V K S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 S944 S S P S P P A S P A D A Q S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 A1554 P G L P P Q H A I S L P P S A
Honey Bee Apis mellifera XP_623857 1936 209316 T1440 P P P P M M L T P P G P H H P
Nematode Worm Caenorhab. elegans Q9BL02 1273 143507 Q873 E Y I L G L S Q G S V S D L L
Sea Urchin Strong. purpuratus XP_780858 1460 163719 K1031 F A V T Q Q V K N L L Q Q H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 83.1 56.2 N.A. 88.8 47.1 N.A. 44.3 77.4 N.A. 40.9 N.A. 23.3 23.7 22.3 29.1
Protein Similarity: 100 98.6 83.4 64.5 N.A. 91.8 50 N.A. 60 81.7 N.A. 55.4 N.A. 37.4 41 41 46.6
P-Site Identity: 100 100 100 6.6 N.A. 100 13.3 N.A. 6.6 100 N.A. 26.6 N.A. 13.3 13.3 13.3 0
P-Site Similarity: 100 100 100 13.3 N.A. 100 26.6 N.A. 13.3 100 N.A. 46.6 N.A. 20 20 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 8 0 0 0 0 8 8 8 8 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 8 0 16 0 8 % D
% Glu: 16 8 39 0 0 8 8 0 0 39 0 0 8 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 8 0 0 0 8 8 8 0 0 0 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 8 16 0 % H
% Ile: 0 0 8 8 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 8 0 0 0 0 39 0 0 % K
% Leu: 0 8 8 8 0 8 16 0 8 8 24 0 8 16 47 % L
% Met: 0 0 0 0 8 47 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % N
% Pro: 24 47 16 24 54 8 8 16 16 8 8 31 8 8 8 % P
% Gln: 0 0 0 0 16 24 0 8 0 0 0 8 16 0 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % R
% Ser: 8 16 8 54 8 0 47 47 47 16 47 8 0 54 24 % S
% Thr: 0 0 0 8 8 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 8 8 0 0 8 39 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _