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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX1
All Species:
20.61
Human Site:
S491
Identified Species:
37.78
UniProt:
P39880
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39880
NP_853530.2
1505
164273
S491
L
Q
R
Q
L
M
Q
S
F
Y
S
K
A
M
Q
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
S502
L
Q
R
Q
L
M
Q
S
F
Y
S
K
A
M
Q
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
S768
L
Q
R
Q
L
M
Q
S
F
Y
S
K
A
M
Q
Dog
Lupus familis
XP_546939
1411
154543
D482
E
K
L
K
G
Q
A
D
Y
E
E
V
K
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P53564
1515
165577
S489
L
Q
R
Q
L
M
Q
S
F
Y
S
K
A
M
Q
Rat
Rattus norvegicus
P53565
862
92341
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
P538
L
P
K
P
M
M
P
P
T
Y
K
S
E
G
G
Chicken
Gallus gallus
XP_425393
1673
183755
S636
L
Q
R
Q
L
M
Q
S
F
Y
S
K
A
M
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693902
1398
154481
S443
L
F
K
K
D
G
S
S
I
M
A
F
P
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10180
2175
233610
S777
Q
L
A
A
S
L
A
S
T
L
N
G
T
K
S
Honey Bee
Apis mellifera
XP_623857
1936
209316
G733
K
A
P
T
P
V
S
G
H
E
T
P
A
P
P
Nematode Worm
Caenorhab. elegans
Q9BL02
1273
143507
V378
I
E
R
L
G
E
T
V
E
T
L
D
R
L
L
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
Q515
H
Q
P
L
P
M
S
Q
S
P
V
P
S
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
83.1
56.2
N.A.
88.8
47.1
N.A.
44.3
77.4
N.A.
40.9
N.A.
23.3
23.7
22.3
29.1
Protein Similarity:
100
98.6
83.4
64.5
N.A.
91.8
50
N.A.
60
81.7
N.A.
55.4
N.A.
37.4
41
41
46.6
P-Site Identity:
100
100
100
0
N.A.
100
0
N.A.
20
100
N.A.
13.3
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
0
N.A.
33.3
100
N.A.
33.3
N.A.
20
20
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
16
0
0
0
8
0
47
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% D
% Glu:
8
8
0
0
0
8
0
0
8
16
8
0
8
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
39
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
16
8
0
8
0
0
0
8
0
8
8
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
8
16
16
0
0
0
0
0
0
8
39
8
16
0
% K
% Leu:
54
8
8
16
39
8
0
0
0
8
8
0
0
8
8
% L
% Met:
0
0
0
0
8
54
0
0
0
8
0
0
0
39
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
16
8
16
0
8
8
0
8
0
16
8
8
8
% P
% Gln:
8
47
0
39
0
8
39
8
0
0
0
0
0
0
39
% Q
% Arg:
0
0
47
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
8
0
24
54
8
0
39
8
8
0
16
% S
% Thr:
0
0
0
8
0
0
8
0
16
8
8
0
8
16
0
% T
% Val:
0
0
0
0
0
8
0
8
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
47
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _