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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP12
All Species:
9.09
Human Site:
Y451
Identified Species:
25
UniProt:
P39900
Number Species:
8
Phosphosite Substitution
Charge Score:
0.63
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39900
NP_002417.2
470
54002
Y451
Q
G
S
N
Q
F
E
Y
D
F
L
L
Q
R
I
Chimpanzee
Pan troglodytes
XP_508724
470
53971
Y451
Q
G
S
N
Q
F
E
Y
D
F
L
L
Q
R
I
Rhesus Macaque
Macaca mulatta
XP_001098589
470
54132
Y451
Q
G
S
N
Q
F
E
Y
D
F
L
L
Q
R
I
Dog
Lupus familis
XP_854594
601
67620
D583
G
P
D
V
F
E
Y
D
V
I
S
H
R
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P34960
473
54953
D455
G
A
Y
Q
L
E
Y
D
P
L
F
R
R
V
T
Rat
Rattus norvegicus
Q63341
465
53720
D447
G
A
Y
Q
L
E
Y
D
P
L
L
D
R
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508976
476
54530
E458
G
S
Q
Q
L
Q
Y
E
P
S
S
K
R
V
T
Chicken
Gallus gallus
XP_417175
496
56924
D478
G
S
N
Q
Y
E
V
D
I
K
N
K
K
L
V
Frog
Xenopus laevis
O13065
467
52794
N449
G
R
S
Q
F
E
Y
N
I
N
S
K
R
I
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
91.2
55.9
N.A.
60
62.3
N.A.
54.4
46.3
46.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
95.9
63.7
N.A.
74.6
76.1
N.A.
69.5
63.7
61.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
0
6.6
N.A.
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
6.6
13.3
N.A.
6.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
45
34
0
0
12
0
0
0
% D
% Glu:
0
0
0
0
0
56
34
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
23
34
0
0
0
34
12
0
0
0
0
% F
% Gly:
67
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
23
12
0
0
0
23
34
% I
% Lys:
0
0
0
0
0
0
0
0
0
12
0
34
12
0
0
% K
% Leu:
0
0
0
0
34
0
0
0
0
23
45
34
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
34
0
0
0
12
0
12
12
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
34
0
0
0
0
0
0
% P
% Gln:
34
0
12
56
34
12
0
0
0
0
0
0
34
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
0
12
56
34
0
% R
% Ser:
0
23
45
0
0
0
0
0
0
12
34
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% T
% Val:
0
0
0
12
0
0
12
0
12
0
0
0
0
34
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
23
0
12
0
56
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _