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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDNF
All Species:
33.03
Human Site:
S164
Identified Species:
90.83
UniProt:
P39905
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39905
NP_000505.1
211
23720
S164
D
K
I
L
K
N
L
S
R
N
R
R
L
V
S
Chimpanzee
Pan troglodytes
XP_001143054
228
25448
S181
D
K
I
L
K
N
L
S
R
N
R
R
L
V
S
Rhesus Macaque
Macaca mulatta
XP_001094714
364
39456
S317
D
K
I
L
K
N
L
S
R
N
R
R
L
V
S
Dog
Lupus familis
XP_546342
265
29007
S218
D
K
I
L
K
N
L
S
K
S
R
R
L
A
S
Cat
Felis silvestris
Mouse
Mus musculus
P48540
211
23644
S164
D
K
I
L
K
N
L
S
R
S
R
R
L
T
S
Rat
Rattus norvegicus
Q07731
211
23601
S164
D
K
I
L
K
N
L
S
R
S
R
R
L
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512363
460
50264
T413
D
K
I
L
K
N
L
T
K
N
N
K
L
A
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q06PM8
227
25753
T180
D
Q
I
L
K
N
L
T
I
R
K
K
L
V
N
Zebra Danio
Brachydanio rerio
Q98TU0
235
26811
T188
D
K
I
L
N
N
L
T
H
N
K
K
L
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
57.4
72.4
N.A.
92.8
92.8
N.A.
37.8
N.A.
59.9
48.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.5
57.6
75.4
N.A.
95.7
95.7
N.A.
42.3
N.A.
74.4
64.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
60
N.A.
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
100
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
89
0
0
89
0
0
0
23
0
23
34
0
0
12
% K
% Leu:
0
0
0
100
0
0
100
0
0
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
100
0
0
0
56
12
0
0
0
23
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
56
12
67
67
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
34
0
0
0
0
67
% S
% Thr:
0
0
0
0
0
0
0
34
0
0
0
0
0
23
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
45
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _