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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCT
All Species:
33.94
Human Site:
T196
Identified Species:
82.96
UniProt:
P40126
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40126
NP_001913.2
519
59145
T196
H
Y
Y
S
V
R
D
T
L
L
G
P
G
R
P
Chimpanzee
Pan troglodytes
XP_520488
537
60736
T199
H
Y
Y
S
V
K
K
T
F
L
G
V
G
Q
E
Rhesus Macaque
Macaca mulatta
XP_001083129
519
59071
T196
H
Y
Y
S
V
R
D
T
L
L
G
P
G
R
P
Dog
Lupus familis
XP_542639
548
62116
T227
H
Y
Y
S
V
R
D
T
L
L
G
P
G
R
P
Cat
Felis silvestris
Mouse
Mus musculus
P29812
517
58551
T196
H
Y
Y
S
V
R
D
T
L
L
G
P
G
R
P
Rat
Rattus norvegicus
XP_224517
466
52772
W163
Y
V
I
T
T
Q
H
W
L
G
L
L
G
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512113
537
61264
T202
H
Y
Y
S
V
R
D
T
L
L
G
P
G
R
P
Chicken
Gallus gallus
O93505
521
59295
T198
H
Y
Y
S
V
R
D
T
L
L
G
P
G
R
P
Frog
Xenopus laevis
NP_001080492
534
60827
T201
H
Y
Y
S
V
S
K
T
F
L
G
P
G
Q
G
Zebra Danio
Brachydanio rerio
NP_571630
513
58237
T192
H
Y
Y
S
V
R
D
T
L
L
G
P
G
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.2
96.3
79.9
N.A.
82.8
75.7
N.A.
70.9
69.4
46
62.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
64.2
98.2
86.1
N.A.
89.5
82.8
N.A.
82.6
82.1
61.4
78.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
100
N.A.
100
13.3
N.A.
100
100
66.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
33.3
N.A.
100
100
73.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
90
0
100
0
10
% G
% His:
90
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
20
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
80
90
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
80
0
10
70
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
20
0
% Q
% Arg:
0
0
0
0
0
70
0
0
0
0
0
0
0
70
0
% R
% Ser:
0
0
0
90
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
10
0
0
90
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
90
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
10
90
90
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _