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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCY8 All Species: 13.03
Human Site: S29 Identified Species: 35.83
UniProt: P40145 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40145 NP_001106.1 1251 140122 S29 P P A G D G R S A S R P Q R L
Chimpanzee Pan troglodytes XP_519960 642 72956
Rhesus Macaque Macaca mulatta XP_001084919 1251 140120 S29 P P A G D G R S A S R P Q R L
Dog Lupus familis XP_539166 1251 139738 G29 P P A G D G G G S A R P Q R L
Cat Felis silvestris
Mouse Mus musculus P97490 1249 140137 S29 P P V G D D G S G S R P Q R L
Rat Rattus norvegicus P40146 1248 139804 S29 P P A A D G G S G S R P Q R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DGG6 1334 149273 I32 S N S V T V R I N P R Q Q Q A
Frog Xenopus laevis P98999 1305 145393 I30 G S S V T V R I N R Q H H Q A
Zebra Danio Brachydanio rerio NP_001137224 1225 138698 S29 P S S S S S S S N N G N R P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51 99.7 97.5 N.A. 96.8 96.9 N.A. N.A. 25.6 27.9 81.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 51.2 99.8 98.6 N.A. 98 98.2 N.A. N.A. 44.5 46.5 89.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 73.3 N.A. 73.3 80 N.A. N.A. 20 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 86.6 N.A. 73.3 80 N.A. N.A. 33.3 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 45 12 0 0 0 0 23 12 0 0 0 0 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 56 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 0 0 45 0 45 34 12 23 0 12 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 12 12 0 0 % H
% Ile: 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 0 34 12 0 12 0 0 0 % N
% Pro: 67 56 0 0 0 0 0 0 0 12 0 56 0 12 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 12 12 67 23 0 % Q
% Arg: 0 0 0 0 0 0 45 0 0 12 67 0 12 56 0 % R
% Ser: 12 23 34 12 12 12 12 56 12 45 0 0 0 0 0 % S
% Thr: 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 12 23 0 23 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _