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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY8
All Species:
19.7
Human Site:
T365
Identified Species:
54.17
UniProt:
P40145
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40145
NP_001106.1
1251
140122
T365
E
A
R
L
R
L
E
T
E
N
Q
R
Q
E
R
Chimpanzee
Pan troglodytes
XP_519960
642
72956
Rhesus Macaque
Macaca mulatta
XP_001084919
1251
140120
T365
E
A
R
L
R
L
E
T
E
N
Q
R
Q
E
R
Dog
Lupus familis
XP_539166
1251
139738
T365
E
A
R
L
R
L
E
T
E
N
Q
R
Q
E
R
Cat
Felis silvestris
Mouse
Mus musculus
P97490
1249
140137
T363
E
A
R
L
R
L
E
T
E
N
Q
R
Q
E
R
Rat
Rattus norvegicus
P40146
1248
139804
T362
E
A
R
L
R
L
E
T
E
N
Q
R
Q
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9DGG6
1334
149273
F386
I
E
Q
V
S
I
L
F
A
D
I
V
G
F
T
Frog
Xenopus laevis
P98999
1305
145393
S362
H
S
A
S
S
P
K
S
R
K
K
K
S
S
I
Zebra Danio
Brachydanio rerio
NP_001137224
1225
138698
N362
F
V
V
L
E
M
I
N
D
M
T
N
V
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
99.7
97.5
N.A.
96.8
96.9
N.A.
N.A.
25.6
27.9
81.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51.2
99.8
98.6
N.A.
98
98.2
N.A.
N.A.
44.5
46.5
89.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
0
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
26.6
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
12
0
0
0
0
0
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
12
% D
% Glu:
56
12
0
0
12
0
56
0
56
0
0
0
0
67
0
% E
% Phe:
12
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
12
12
0
0
0
12
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
12
0
0
12
12
12
0
0
0
% K
% Leu:
0
0
0
67
0
56
12
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
56
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
56
0
56
0
0
% Q
% Arg:
0
0
56
0
56
0
0
0
12
0
0
56
0
0
56
% R
% Ser:
0
12
0
12
23
0
0
12
0
0
0
0
12
12
0
% S
% Thr:
0
0
0
0
0
0
0
56
0
0
12
0
0
0
12
% T
% Val:
0
12
12
12
0
0
0
0
0
0
0
12
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _