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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXLNA All Species: 11.21
Human Site: T497 Identified Species: 24.67
UniProt: P40222 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40222 NP_787048.1 546 61891 T497 A G G Q G S L T D S G P E R R
Chimpanzee Pan troglodytes XP_513277 417 47648 S369 L L K E A V E S Q R M C E L M
Rhesus Macaque Macaca mulatta XP_001096131 411 47867 D363 G G Q G S L T D S G P E R R P
Dog Lupus familis XP_544439 550 62005 T501 A G G Q G S I T D G G P E R R
Cat Felis silvestris
Mouse Mus musculus Q6PAM1 554 62350 T505 S E R R P E A T T A S K E Q G
Rat Rattus norvegicus NP_001121105 557 62548 T497 A G G Q G S L T D T G S E R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506387 954 104037 Q905 K V Q D L S A Q A P L Q D P A
Chicken Gallus gallus Q9I969 676 77002 N468 L P E E V N G N D I L E E D D
Frog Xenopus laevis NP_001090396 513 59025 A465 N L C K S L E A P P G Q L V T
Zebra Danio Brachydanio rerio NP_001092700 514 58746 D461 T G A E S R L D T E S G S P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780699 544 61541 P479 K A R T D E T P S S A S D L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76 72.1 93.6 N.A. 88.2 88.1 N.A. 46.7 44.5 67 63.3 N.A. N.A. N.A. N.A. 42.1
Protein Similarity: 100 76 73.4 95.2 N.A. 90.7 91.5 N.A. 49.7 57.6 75.8 74.1 N.A. N.A. N.A. N.A. 60.8
P-Site Identity: 100 6.6 13.3 86.6 N.A. 13.3 86.6 N.A. 6.6 13.3 6.6 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 20 13.3 93.3 N.A. 40 93.3 N.A. 13.3 26.6 13.3 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 10 10 0 10 0 19 10 10 10 10 0 0 0 10 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 10 10 0 0 19 37 0 0 0 19 10 10 % D
% Glu: 0 10 10 28 0 19 19 0 0 10 0 19 55 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 46 28 10 28 0 10 0 0 19 37 10 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % I
% Lys: 19 0 10 10 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 19 19 0 0 10 19 28 0 0 0 19 0 10 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % M
% Asn: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 10 0 0 10 10 19 10 19 0 19 19 % P
% Gln: 0 0 19 28 0 0 0 10 10 0 0 19 0 10 0 % Q
% Arg: 0 0 19 10 0 10 0 0 0 10 0 0 10 37 28 % R
% Ser: 10 0 0 0 28 37 0 10 19 19 19 19 10 0 0 % S
% Thr: 10 0 0 10 0 0 19 37 19 10 0 0 0 0 10 % T
% Val: 0 10 0 0 10 10 0 0 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _