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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCT6A
All Species:
29.7
Human Site:
S246
Identified Species:
59.39
UniProt:
P40227
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40227
NP_001753.1
531
58024
S246
Y
E
K
T
E
V
N
S
G
F
F
Y
K
S
A
Chimpanzee
Pan troglodytes
XP_001159199
494
53808
R227
E
K
L
V
K
A
E
R
K
F
I
E
D
R
V
Rhesus Macaque
Macaca mulatta
XP_001090105
531
57923
S246
Y
E
K
T
E
V
S
S
G
F
F
Y
K
S
A
Dog
Lupus familis
XP_548266
531
57819
S246
Y
E
K
T
E
V
S
S
G
F
F
Y
K
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P80317
531
57986
S246
Y
E
K
T
E
V
N
S
G
F
F
Y
K
S
A
Rat
Rattus norvegicus
Q6P502
545
60628
T254
Y
K
K
G
E
S
Q
T
D
I
E
I
T
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517997
464
50672
K220
K
V
C
G
D
S
D
K
G
F
V
V
I
N
Q
Chicken
Gallus gallus
Q5ZJ54
530
57626
A245
Y
E
K
T
E
V
S
A
G
F
F
Y
K
S
A
Frog
Xenopus laevis
P50143
547
60618
T253
Y
K
K
G
E
S
Q
T
E
I
E
I
T
R
E
Zebra Danio
Brachydanio rerio
NP_958447
531
57610
S246
Y
E
K
T
E
V
N
S
G
F
F
Y
K
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46550
539
58886
S246
Y
E
K
T
E
V
N
S
G
L
F
Y
K
T
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39079
546
59905
S249
Y
E
K
T
E
V
N
S
G
F
F
Y
S
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
96.4
87
N.A.
96.8
27.5
N.A.
80.4
89.8
27.9
87.5
N.A.
N.A.
N.A.
66.2
N.A.
Protein Similarity:
100
93
97.7
94.3
N.A.
100
54.8
N.A.
85.5
96.4
53.3
95.4
N.A.
N.A.
N.A.
80.3
N.A.
P-Site Identity:
100
6.6
93.3
86.6
N.A.
100
20
N.A.
13.3
86.6
20
100
N.A.
N.A.
N.A.
86.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
33.3
N.A.
33.3
100
33.3
100
N.A.
N.A.
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
56.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
74.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
67
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
9
0
9
0
0
0
9
0
0
% D
% Glu:
9
67
0
0
84
0
9
0
9
0
17
9
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
75
67
0
0
0
0
% F
% Gly:
0
0
0
25
0
0
0
0
75
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
17
9
17
9
0
0
% I
% Lys:
9
25
84
0
9
0
0
9
9
0
0
0
59
0
0
% K
% Leu:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
42
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
25
0
% R
% Ser:
0
0
0
0
0
25
25
59
0
0
0
0
9
50
0
% S
% Thr:
0
0
0
67
0
0
0
17
0
0
0
0
17
17
0
% T
% Val:
0
9
0
9
0
67
0
0
0
0
9
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
84
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _