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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCT6A All Species: 30.91
Human Site: S252 Identified Species: 61.82
UniProt: P40227 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40227 NP_001753.1 531 58024 S252 N S G F F Y K S A E E R E K L
Chimpanzee Pan troglodytes XP_001159199 494 53808 R233 E R K F I E D R V K K I I E L
Rhesus Macaque Macaca mulatta XP_001090105 531 57923 S252 S S G F F Y K S A E E R E K L
Dog Lupus familis XP_548266 531 57819 T252 S S G F F Y K T A E E K E K L
Cat Felis silvestris
Mouse Mus musculus P80317 531 57986 S252 N S G F F Y K S A E E R E K L
Rat Rattus norvegicus Q6P502 545 60628 R260 Q T D I E I T R E E D F T R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517997 464 50672 N226 D K G F V V I N Q K G I D P F
Chicken Gallus gallus Q5ZJ54 530 57626 S251 S A G F F Y K S A E E R E K L
Frog Xenopus laevis P50143 547 60618 R259 Q T E I E I T R E E D F A R I
Zebra Danio Brachydanio rerio NP_958447 531 57610 S252 N S G F F Y K S A D E R D K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46550 539 58886 T252 N S G L F Y K T A K E R E A L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39079 546 59905 S255 N S G F F Y S S A D Q R D K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 96.4 87 N.A. 96.8 27.5 N.A. 80.4 89.8 27.9 87.5 N.A. N.A. N.A. 66.2 N.A.
Protein Similarity: 100 93 97.7 94.3 N.A. 100 54.8 N.A. 85.5 96.4 53.3 95.4 N.A. N.A. N.A. 80.3 N.A.
P-Site Identity: 100 13.3 93.3 80 N.A. 100 6.6 N.A. 13.3 86.6 6.6 86.6 N.A. N.A. N.A. 73.3 N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 100 33.3 N.A. 40 100 33.3 100 N.A. N.A. N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 56.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 74.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 67 0 0 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 0 0 9 0 0 17 17 0 25 0 0 % D
% Glu: 9 0 9 0 17 9 0 0 17 59 59 0 50 9 0 % E
% Phe: 0 0 0 75 67 0 0 0 0 0 0 17 0 0 9 % F
% Gly: 0 0 75 0 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 17 9 17 9 0 0 0 0 17 9 0 17 % I
% Lys: 0 9 9 0 0 0 59 0 0 25 9 9 0 59 0 % K
% Leu: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 75 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 42 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 17 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % Q
% Arg: 0 9 0 0 0 0 0 25 0 0 0 59 0 17 0 % R
% Ser: 25 59 0 0 0 0 9 50 0 0 0 0 0 0 0 % S
% Thr: 0 17 0 0 0 0 17 17 0 0 0 0 9 0 0 % T
% Val: 0 0 0 0 9 9 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _