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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCT6A All Species: 32.42
Human Site: Y498 Identified Species: 64.85
UniProt: P40227 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40227 NP_001753.1 531 58024 Y498 E V G V W D N Y C V K K Q L L
Chimpanzee Pan troglodytes XP_001159199 494 53808 Y461 E V G V W D N Y C V K K Q L L
Rhesus Macaque Macaca mulatta XP_001090105 531 57923 Y498 E V G V W D N Y C V K K Q L L
Dog Lupus familis XP_548266 531 57819 Y498 D A G V W D N Y C V K K Q L L
Cat Felis silvestris
Mouse Mus musculus P80317 531 57986 Y498 E M G V W D N Y C V K K Q L L
Rat Rattus norvegicus Q6P502 545 60628 L499 E L G I W E P L A V K L Q T Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517997 464 50672 Y431 E A G V W D N Y C V K K Q L L
Chicken Gallus gallus Q5ZJ54 530 57626 Y497 A A G I W D N Y N V K K Q L L
Frog Xenopus laevis P50143 547 60618 L498 E L G I W E P L A V K L Q T Y
Zebra Danio Brachydanio rerio NP_958447 531 57610 Y498 E A G V W D N Y S V K K Q L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46550 539 58886 V502 P Q G I W D N V T V K K N S I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39079 546 59905 Y510 I E G I W D S Y R V L R N A I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 96.4 87 N.A. 96.8 27.5 N.A. 80.4 89.8 27.9 87.5 N.A. N.A. N.A. 66.2 N.A.
Protein Similarity: 100 93 97.7 94.3 N.A. 100 54.8 N.A. 85.5 96.4 53.3 95.4 N.A. N.A. N.A. 80.3 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 93.3 40 N.A. 93.3 73.3 40 86.6 N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 60 N.A. 93.3 80 60 86.6 N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 56.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 74.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 34 0 0 0 0 0 0 17 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 84 0 0 0 0 0 0 0 0 0 % D
% Glu: 67 9 0 0 0 17 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 42 0 0 0 0 0 0 0 0 0 0 17 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 92 75 0 0 0 % K
% Leu: 0 17 0 0 0 0 0 17 0 0 9 17 0 67 67 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 75 0 9 0 0 0 17 0 0 % N
% Pro: 9 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 84 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % R
% Ser: 0 0 0 0 0 0 9 0 9 0 0 0 0 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 9 0 0 0 0 17 0 % T
% Val: 0 25 0 59 0 0 0 9 0 100 0 0 0 0 0 % V
% Trp: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _