KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMB10
All Species:
10.3
Human Site:
T227
Identified Species:
16.19
UniProt:
P40306
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40306
NP_002792.1
273
28936
T227
T
G
A
K
L
L
R
T
L
S
S
P
T
E
P
Chimpanzee
Pan troglodytes
XP_520247
277
29919
P231
N
K
L
D
F
L
R
P
Y
T
V
P
N
K
K
Rhesus Macaque
Macaca mulatta
XP_001095570
273
28888
T227
T
G
A
K
L
L
R
T
L
S
S
P
T
E
P
Dog
Lupus familis
XP_546869
305
32610
T259
T
G
A
K
L
L
R
T
L
S
S
P
T
K
P
Cat
Felis silvestris
Mouse
Mus musculus
O35955
273
29045
A227
G
G
A
K
L
Q
R
A
L
S
T
P
T
E
P
Rat
Rattus norvegicus
Q9JHW0
277
29909
P231
S
K
L
D
F
L
R
P
Y
S
V
P
N
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505328
263
28364
P217
E
G
I
R
S
H
R
P
Y
G
I
H
G
R
K
Chicken
Gallus gallus
NP_989728
277
29858
P231
N
K
L
D
F
I
R
P
Y
D
V
A
N
R
K
Frog
Xenopus laevis
NP_001079861
279
30075
G232
E
E
A
R
V
L
R
G
H
T
N
T
E
T
R
Zebra Danio
Brachydanio rerio
NP_001002543
276
29828
T230
K
K
V
D
Y
L
R
T
Y
D
Q
P
V
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391905
277
30287
P227
G
S
V
D
Y
L
R
P
Y
D
V
A
N
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793038
273
29401
P227
G
K
V
D
F
L
R
P
Y
D
V
A
N
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001149857
273
29162
N226
G
K
T
E
Y
L
R
N
H
Q
L
P
N
P
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7DLS1
274
29598
N227
G
H
K
E
Y
L
R
N
Y
M
E
P
N
P
R
Baker's Yeast
Sacchar. cerevisiae
P25043
261
28249
L216
I
G
K
D
A
E
Y
L
R
N
Y
L
T
P
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.6
96.6
76
N.A.
88.6
57
N.A.
60
55.9
59.1
62.3
N.A.
N.A.
49.4
N.A.
56.7
Protein Similarity:
100
74.3
97.8
82.6
N.A.
93.4
74
N.A.
72.5
72.5
73.8
76.4
N.A.
N.A.
67.8
N.A.
71.4
P-Site Identity:
100
20
100
93.3
N.A.
73.3
26.6
N.A.
13.3
6.6
20
26.6
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
33.3
100
100
N.A.
80
40
N.A.
20
13.3
46.6
26.6
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
53.8
N.A.
50.3
45
N.A.
Protein Similarity:
N.A.
67
N.A.
67.1
61.5
N.A.
P-Site Identity:
N.A.
20
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
0
7
0
0
7
0
0
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
47
0
0
0
0
0
27
0
0
0
0
0
% D
% Glu:
14
7
0
14
0
7
0
0
0
0
7
0
7
20
0
% E
% Phe:
0
0
0
0
27
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
40
0
0
0
0
0
7
0
7
0
0
7
0
0
% G
% His:
0
7
0
0
0
7
0
0
14
0
0
7
0
7
0
% H
% Ile:
7
0
7
0
0
7
0
0
0
0
7
0
0
0
0
% I
% Lys:
7
40
14
27
0
0
0
0
0
0
0
0
0
27
47
% K
% Leu:
0
0
20
0
27
74
0
7
27
0
7
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
14
0
0
0
0
0
0
14
0
7
7
0
47
0
7
% N
% Pro:
0
0
0
0
0
0
0
40
0
0
0
60
0
20
27
% P
% Gln:
0
0
0
0
0
7
0
0
0
7
7
0
0
0
0
% Q
% Arg:
0
0
0
14
0
0
94
0
7
0
0
0
0
14
20
% R
% Ser:
7
7
0
0
7
0
0
0
0
34
20
0
0
0
0
% S
% Thr:
20
0
7
0
0
0
0
27
0
14
7
7
34
7
0
% T
% Val:
0
0
20
0
7
0
0
0
0
0
34
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
27
0
7
0
54
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _