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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTRL All Species: 13.03
Human Site: T248 Identified Species: 31.85
UniProt: P40313 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.67
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40313 NP_001898.1 264 28002 T248 V R A P A V Y T R V S K F S T
Chimpanzee Pan troglodytes XP_511044 299 31909 T283 V R A P A V Y T R V S K F S T
Rhesus Macaque Macaca mulatta O19023 257 27669 R242 R K P T V F T R V S A F I D W
Dog Lupus familis XP_853830 264 28200 T248 V R Q P A I Y T R V S K F S T
Cat Felis silvestris
Mouse Mus musculus Q9CR35 263 27803 R248 S T P A V Y A R V T A L M P W
Rat Rattus norvegicus P07338 263 27830 R248 S T P A V Y S R V T A L M P W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505529 265 28417 T249 V S S P A M Y T R V S K F S T
Chicken Gallus gallus Q90629 248 26604 K233 G Y P G V Y T K V C N Y V D W
Frog Xenopus laevis NP_001079805 263 27719 R248 S S P G V Y A R V S T L R S W
Zebra Danio Brachydanio rerio NP_001004582 261 27868 R246 R T P A V Y A R V S Y L R Q W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 42 89 N.A. 53 52.2 N.A. 72.8 41.6 59 62.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87.6 57.2 93.5 N.A. 69.6 68.1 N.A. 84.5 55.2 74.2 77.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 86.6 N.A. 0 0 N.A. 80 0 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 6.6 6.6 N.A. 93.3 6.6 13.3 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 30 40 0 30 0 0 0 30 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 10 40 0 0 % F
% Gly: 10 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 10 0 0 0 0 0 10 0 0 0 40 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 40 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 20 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 60 40 0 0 0 0 0 0 0 0 0 20 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 20 30 0 0 0 0 0 50 40 0 0 0 20 0 0 % R
% Ser: 30 20 10 0 0 0 10 0 0 30 40 0 0 50 0 % S
% Thr: 0 30 0 10 0 0 20 40 0 20 10 0 0 0 40 % T
% Val: 40 0 0 0 60 20 0 0 60 40 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 % W
% Tyr: 0 10 0 0 0 50 40 0 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _