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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTRL All Species: 14.24
Human Site: Y247 Identified Species: 34.81
UniProt: P40313 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40313 NP_001898.1 264 28002 Y247 N V R A P A V Y T R V S K F S
Chimpanzee Pan troglodytes XP_511044 299 31909 Y282 N V R A P A V Y T R V S K F S
Rhesus Macaque Macaca mulatta O19023 257 27669 T241 Q R K P T V F T R V S A F I D
Dog Lupus familis XP_853830 264 28200 Y247 N V R Q P A I Y T R V S K F S
Cat Felis silvestris
Mouse Mus musculus Q9CR35 263 27803 A247 T S T P A V Y A R V T A L M P
Rat Rattus norvegicus P07338 263 27830 S247 T S T P A V Y S R V T A L M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505529 265 28417 Y248 D V S S P A M Y T R V S K F S
Chicken Gallus gallus Q90629 248 26604 T232 K G Y P G V Y T K V C N Y V D
Frog Xenopus laevis NP_001079805 263 27719 A247 P S S P G V Y A R V S T L R S
Zebra Danio Brachydanio rerio NP_001004582 261 27868 A245 V R T P A V Y A R V S Y L R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 42 89 N.A. 53 52.2 N.A. 72.8 41.6 59 62.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87.6 57.2 93.5 N.A. 69.6 68.1 N.A. 84.5 55.2 74.2 77.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 86.6 N.A. 0 0 N.A. 73.3 0 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 6.6 6.6 N.A. 93.3 6.6 13.3 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 30 40 0 30 0 0 0 30 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 10 40 0 % F
% Gly: 0 10 0 0 20 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % I
% Lys: 10 0 10 0 0 0 0 0 10 0 0 0 40 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 20 0 % M
% Asn: 30 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 10 0 0 60 40 0 0 0 0 0 0 0 0 0 20 % P
% Gln: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 20 30 0 0 0 0 0 50 40 0 0 0 20 0 % R
% Ser: 0 30 20 10 0 0 0 10 0 0 30 40 0 0 50 % S
% Thr: 20 0 30 0 10 0 0 20 40 0 20 10 0 0 0 % T
% Val: 10 40 0 0 0 60 20 0 0 60 40 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 50 40 0 0 0 10 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _