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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VHL
All Species:
0
Human Site:
S43
Identified Species:
0
UniProt:
P40337
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40337
NP_000542.1
213
24153
S43
E
E
S
G
P
E
E
S
G
P
E
E
L
G
A
Chimpanzee
Pan troglodytes
XP_001171363
190
20804
L28
P
F
A
H
A
H
S
L
R
P
A
I
S
A
S
Rhesus Macaque
Macaca mulatta
XP_001090152
129
14460
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P40338
181
20751
P27
M
E
A
G
R
P
R
P
V
L
R
S
V
N
S
Rat
Rattus norvegicus
Q64259
185
21197
R30
G
R
P
R
P
V
L
R
S
V
N
S
R
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505708
183
20745
W29
T
N
S
S
G
P
F
W
R
F
K
P
L
S
A
Chicken
Gallus gallus
XP_414447
166
19213
R12
A
A
A
Q
L
A
L
R
S
A
G
P
C
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074153
175
20424
I19
L
P
L
V
R
S
L
I
S
R
I
Q
V
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
52.5
N.A.
N.A.
74.6
76
N.A.
37.5
52.1
N.A.
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.6
57.2
N.A.
N.A.
80.2
81.2
N.A.
52.1
64.7
N.A.
55.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
N.A.
N.A.
13.3
6.6
N.A.
20
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
0
N.A.
N.A.
33.3
6.6
N.A.
26.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
38
0
13
13
0
0
0
13
13
0
0
13
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
13
25
0
0
0
13
13
0
0
0
13
13
0
13
0
% E
% Phe:
0
13
0
0
0
0
13
0
0
13
0
0
0
0
0
% F
% Gly:
13
0
0
25
13
0
0
0
13
0
13
0
0
13
0
% G
% His:
0
0
0
13
0
13
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
13
13
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% K
% Leu:
13
0
13
0
13
0
38
13
0
13
0
0
25
13
0
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
13
0
0
25
0
% N
% Pro:
13
13
13
0
25
25
0
13
0
25
0
25
0
0
13
% P
% Gln:
0
0
0
13
0
0
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
13
0
13
25
0
13
25
25
13
13
0
13
0
13
% R
% Ser:
0
0
25
13
0
13
13
13
38
0
0
25
13
13
25
% S
% Thr:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
13
0
13
0
0
13
13
0
0
25
0
13
% V
% Trp:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _