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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PBX2
All Species:
19.39
Human Site:
S423
Identified Species:
35.56
UniProt:
P40425
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40425
NP_002577.2
430
45881
S423
S
P
T
E
G
P
G
S
V
H
S
D
T
S
N
Chimpanzee
Pan troglodytes
XP_001163104
443
47321
T423
G
S
W
Q
E
A
V
T
P
S
S
V
T
S
P
Rhesus Macaque
Macaca mulatta
XP_001084010
407
44166
G397
S
V
T
S
P
T
E
G
P
G
S
V
H
S
D
Dog
Lupus familis
XP_850252
426
45439
S419
S
P
T
E
G
P
G
S
V
H
S
D
T
S
N
Cat
Felis silvestris
Mouse
Mus musculus
O35984
430
45791
S423
S
P
T
E
G
P
G
S
V
H
S
D
T
S
N
Rat
Rattus norvegicus
NP_001002828
430
45809
S423
S
P
T
E
G
P
G
S
V
H
S
D
T
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508896
400
44150
T380
G
G
W
Q
D
P
T
T
P
S
S
V
T
S
P
Chicken
Gallus gallus
NP_001025849
433
47074
T413
G
G
W
Q
D
A
T
T
P
S
S
V
T
S
P
Frog
Xenopus laevis
Q6IR52
445
49385
L416
L
F
T
W
T
K
P
L
P
R
L
T
P
I
L
Zebra Danio
Brachydanio rerio
NP_001077322
429
46552
S411
W
Q
D
P
T
T
P
S
S
V
T
S
P
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40427
376
41673
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41779
338
38136
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJ56
680
74445
G564
Y
P
F
M
G
N
F
G
Q
Y
Q
M
D
E
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
73.7
97.2
N.A.
97.9
98.1
N.A.
65.8
77.3
71
76.2
N.A.
63.4
N.A.
48.3
N.A.
Protein Similarity:
100
97
81.6
97.4
N.A.
98.5
98.5
N.A.
74.4
83.1
77.7
84.4
N.A.
72.5
N.A.
61.1
N.A.
P-Site Identity:
100
20
26.6
100
N.A.
100
100
N.A.
26.6
20
6.6
6.6
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
100
N.A.
40
33.3
6.6
20
N.A.
0
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
16
0
0
0
0
0
0
31
8
0
8
% D
% Glu:
0
0
0
31
8
0
8
0
0
0
0
0
0
8
8
% E
% Phe:
0
8
8
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
24
16
0
0
39
0
31
16
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
31
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
31
% N
% Pro:
0
39
0
8
8
39
16
0
39
0
0
0
16
0
24
% P
% Gln:
0
8
0
24
0
0
0
0
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
39
8
0
8
0
0
0
39
8
24
62
8
0
62
0
% S
% Thr:
0
0
47
0
16
16
16
24
0
0
8
8
54
8
0
% T
% Val:
0
8
0
0
0
0
8
0
31
8
0
31
0
0
0
% V
% Trp:
8
0
24
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _