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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PBX3
All Species:
22.73
Human Site:
Y253
Identified Species:
45.45
UniProt:
P40426
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40426
NP_001128250.1
434
47190
Y253
A
T
E
I
L
N
E
Y
F
Y
S
H
L
S
N
Chimpanzee
Pan troglodytes
XP_520261
434
46952
Y253
A
T
E
I
L
N
E
Y
F
Y
S
H
L
S
N
Rhesus Macaque
Macaca mulatta
XP_001084131
430
46596
N249
K
Q
A
T
E
I
L
N
E
Y
F
Y
S
H
L
Dog
Lupus familis
XP_545786
430
46577
N249
K
Q
A
T
E
I
L
N
E
Y
F
Y
S
H
L
Cat
Felis silvestris
Mouse
Mus musculus
O35317
434
47185
Y253
A
T
E
I
L
N
E
Y
F
Y
S
H
L
S
N
Rat
Rattus norvegicus
NP_001002828
430
45809
R249
L
D
A
R
R
K
R
R
N
F
S
K
Q
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508896
400
44150
Y219
A
T
E
I
L
N
E
Y
F
Y
S
H
L
S
N
Chicken
Gallus gallus
NP_001025849
433
47074
Y252
A
T
E
I
L
N
E
Y
F
Y
S
H
L
S
N
Frog
Xenopus laevis
Q6IR52
445
49385
Y255
A
T
E
V
L
N
E
Y
F
Y
S
H
L
S
N
Zebra Danio
Brachydanio rerio
NP_001077322
429
46552
N248
K
Q
A
T
E
I
L
N
E
Y
F
Y
S
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40427
376
41673
R195
L
R
E
Q
S
R
T
R
P
I
T
P
K
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41779
338
38136
I158
E
I
E
R
M
V
Y
I
I
Q
R
K
F
N
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.1
81.5
84.5
N.A.
99.7
77.1
N.A.
81.5
99.3
67.8
85.2
N.A.
63.5
N.A.
48.3
N.A.
Protein Similarity:
100
96
88.4
90.7
N.A.
99.7
83.6
N.A.
84.7
99.7
75
91.4
N.A.
72.3
N.A.
60.3
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
100
6.6
N.A.
100
100
93.3
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
20
N.A.
100
100
100
13.3
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
34
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
67
0
25
0
50
0
25
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
50
9
25
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
50
0
25
0
% H
% Ile:
0
9
0
42
0
25
0
9
9
9
0
0
0
0
9
% I
% Lys:
25
0
0
0
0
9
0
0
0
0
0
17
9
0
0
% K
% Leu:
17
0
0
0
50
0
25
0
0
0
0
0
50
0
25
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
50
0
25
9
0
0
0
0
9
50
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% P
% Gln:
0
25
0
9
0
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
9
0
17
9
9
9
17
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
0
0
0
59
0
25
50
0
% S
% Thr:
0
50
0
25
0
0
9
0
0
0
9
0
0
0
9
% T
% Val:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
50
0
75
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _