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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARL1
All Species:
22.42
Human Site:
T135
Identified Species:
35.24
UniProt:
P40616
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40616
NP_001168.1
181
20418
T135
Q
D
M
E
Q
A
M
T
S
S
E
M
A
N
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001084102
156
17740
S111
D
M
E
Q
A
M
T
S
S
E
M
A
N
S
L
Dog
Lupus familis
XP_866656
135
15434
S91
M
E
Q
A
M
T
P
S
E
M
A
N
S
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P61212
181
20393
T135
Q
D
M
E
Q
A
M
T
P
S
E
M
A
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49702
180
20461
V135
Q
D
M
P
N
A
M
V
V
S
E
L
T
D
K
Frog
Xenopus laevis
P51643
181
20696
N135
Q
D
L
P
N
A
M
N
A
A
E
I
T
D
K
Zebra Danio
Brachydanio rerio
NP_001002473
181
20305
T135
Q
D
M
E
Q
A
M
T
P
T
E
V
A
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25160
180
20229
T134
Q
D
M
D
G
C
M
T
V
A
E
V
H
H
A
Honey Bee
Apis mellifera
XP_001120141
180
20157
S134
Q
D
M
A
G
C
L
S
V
A
E
V
H
Q
A
Nematode Worm
Caenorhab. elegans
Q20758
180
20086
T134
Q
D
I
A
G
C
L
T
E
T
E
V
Y
K
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309696
182
20166
D135
Q
D
L
P
G
A
L
D
A
A
A
V
T
E
A
Maize
Zea mays
P49076
181
20642
N135
Q
D
L
P
N
A
M
N
A
A
E
I
T
D
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P40940
182
20224
D135
Q
D
L
P
G
A
L
D
D
A
A
V
T
E
A
Baker's Yeast
Sacchar. cerevisiae
P38116
183
20416
S136
Q
D
Q
P
G
A
L
S
A
S
E
V
S
K
E
Red Bread Mold
Neurospora crassa
Q7RVM2
185
20961
N138
Q
D
L
P
N
A
M
N
A
A
E
I
T
D
K
Conservation
Percent
Protein Identity:
100
N.A.
76.2
74
N.A.
N.A.
98.9
N.A.
N.A.
59.1
56.9
94.4
N.A.
78.4
76.8
71.8
N.A.
Protein Similarity:
100
N.A.
81.7
74
N.A.
N.A.
99.4
N.A.
N.A.
76.2
76.8
98.3
N.A.
86.1
86.1
82.8
N.A.
P-Site Identity:
100
N.A.
6.6
0
N.A.
N.A.
86.6
N.A.
N.A.
46.6
33.3
73.3
N.A.
40
26.6
26.6
N.A.
P-Site Similarity:
100
N.A.
26.6
20
N.A.
N.A.
93.3
N.A.
N.A.
60
66.6
93.3
N.A.
73.3
60
60
N.A.
Percent
Protein Identity:
65.3
56.9
N.A.
64.2
63.3
57.3
Protein Similarity:
79.6
74.5
N.A.
79.1
79.2
72.9
P-Site Identity:
20
33.3
N.A.
20
33.3
33.3
P-Site Similarity:
60
66.6
N.A.
53.3
66.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
7
67
0
0
34
47
20
7
20
0
47
% A
% Cys:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
87
0
7
0
0
0
14
7
0
0
0
0
27
0
% D
% Glu:
0
7
7
20
0
0
0
0
14
7
74
0
0
14
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
14
7
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
20
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
27
% K
% Leu:
0
0
34
0
0
0
34
0
0
0
0
7
0
7
7
% L
% Met:
7
7
40
0
7
7
54
0
0
7
7
14
0
0
0
% M
% Asn:
0
0
0
0
27
0
0
20
0
0
0
7
7
20
0
% N
% Pro:
0
0
0
47
0
0
7
0
14
0
0
0
0
0
0
% P
% Gln:
87
0
14
7
20
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
27
14
27
0
0
14
7
7
% S
% Thr:
0
0
0
0
0
7
7
34
0
14
0
0
40
0
0
% T
% Val:
0
0
0
0
0
0
0
7
20
0
0
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _