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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARL4A
All Species:
22.12
Human Site:
S122
Identified Species:
28.63
UniProt:
P40617
Number Species:
17
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40617
NP_001032241.1
200
22615
S122
L
H
K
I
T
R
I
S
E
N
Q
G
V
P
V
Chimpanzee
Pan troglodytes
XP_001147147
220
24954
S122
L
H
K
I
T
R
I
S
E
N
Q
G
V
P
V
Rhesus Macaque
Macaca mulatta
XP_001099050
200
22556
S122
L
H
K
I
T
R
I
S
E
N
Q
G
V
P
V
Dog
Lupus familis
XP_548073
201
22148
S123
L
H
R
I
S
R
A
S
D
N
Q
G
V
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99PE9
201
22223
S123
L
H
R
I
S
K
A
S
D
N
Q
G
V
P
V
Rat
Rattus norvegicus
P61214
200
22570
S122
L
H
K
I
T
R
I
S
E
N
Q
G
V
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519864
193
21567
Q119
V
T
K
F
A
E
N
Q
G
T
P
L
L
V
I
Chicken
Gallus gallus
P26990
175
20078
D125
L
I
F
A
N
K
Q
D
L
P
D
A
M
K
P
Frog
Xenopus laevis
P51644
180
20567
N126
A
V
L
L
V
F
A
N
K
Q
D
L
P
N
A
Zebra Danio
Brachydanio rerio
NP_956612
201
22867
Q123
L
H
K
I
T
R
L
Q
E
N
L
G
V
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40946
175
19987
N122
A
I
I
L
I
F
A
N
K
Q
D
L
P
D
A
Honey Bee
Apis mellifera
XP_001120491
207
22359
P125
L
T
R
T
A
R
S
P
D
N
A
G
V
P
I
Nematode Worm
Caenorhab. elegans
Q10943
181
20503
N126
A
V
L
L
V
F
A
N
K
Q
D
L
P
Q
A
Sea Urchin
Strong. purpuratus
XP_785283
193
21506
D129
M
L
I
A
N
K
Q
D
L
R
Q
A
V
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49076
181
20642
N126
A
V
L
L
V
F
A
N
K
Q
D
L
P
N
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SHU5
205
23062
N141
L
P
V
A
E
V
A
N
K
L
G
L
H
S
L
Baker's Yeast
Sacchar. cerevisiae
P11076
181
20511
V123
L
R
N
A
A
W
L
V
F
A
N
K
Q
D
L
Red Bread Mold
Neurospora crassa
Q7RVM2
185
20961
D121
L
N
E
D
E
L
R
D
A
L
L
L
V
F
A
Conservation
Percent
Protein Identity:
100
89
99
60.2
N.A.
60.7
99.5
N.A.
68
42
42.5
80
N.A.
42
54.1
40
50.5
Protein Similarity:
100
90.9
99.5
80
N.A.
81
100
N.A.
85.5
58
62
89.5
N.A.
59
70.5
59.5
69.5
P-Site Identity:
100
100
100
73.3
N.A.
66.6
100
N.A.
6.6
6.6
0
80
N.A.
0
40
0
20
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
26.6
20
20
86.6
N.A.
20
60
20
33.3
Percent
Protein Identity:
N.A.
40.5
N.A.
43.4
39.5
42
Protein Similarity:
N.A.
60.5
N.A.
59.5
58
60
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
13.3
P-Site Similarity:
N.A.
20
N.A.
26.6
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
23
17
0
39
0
6
6
6
12
0
0
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
0
0
0
17
17
0
28
0
0
12
0
% D
% Glu:
0
0
6
0
12
6
0
0
28
0
0
0
0
0
0
% E
% Phe:
0
0
6
6
0
23
0
0
6
0
0
0
0
6
0
% F
% Gly:
0
0
0
0
0
0
0
0
6
0
6
45
0
6
0
% G
% His:
0
39
0
0
0
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
0
12
12
39
6
0
23
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
34
0
0
17
0
0
28
0
0
6
0
6
0
% K
% Leu:
67
6
17
23
0
6
12
0
12
12
12
39
6
0
12
% L
% Met:
6
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
6
6
0
12
0
6
28
0
45
6
0
0
12
0
% N
% Pro:
0
6
0
0
0
0
0
6
0
6
6
0
23
45
6
% P
% Gln:
0
0
0
0
0
0
12
12
0
23
39
0
6
6
0
% Q
% Arg:
0
6
17
0
0
39
6
0
0
6
0
0
0
0
0
% R
% Ser:
0
0
0
0
12
0
6
34
0
0
0
0
0
6
0
% S
% Thr:
0
12
0
6
28
0
0
0
0
6
0
0
0
0
0
% T
% Val:
6
17
6
0
17
6
0
6
0
0
0
0
56
6
45
% V
% Trp:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _