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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL4A All Species: 18.79
Human Site: S159 Identified Species: 24.31
UniProt: P40617 Number Species: 17
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40617 NP_001032241.1 200 22615 S159 A M G E L S S S T P W H L Q P
Chimpanzee Pan troglodytes XP_001147147 220 24954 S159 A M G D L S S S T P W H L Q P
Rhesus Macaque Macaca mulatta XP_001099050 200 22556 S159 A M G E L S S S T P W H L Q P
Dog Lupus familis XP_548073 201 22148 A160 A V R E L A A A T L T H V Q G
Cat Felis silvestris
Mouse Mus musculus Q99PE9 201 22223 A160 A V R E L A A A T L T H V Q A
Rat Rattus norvegicus P61214 200 22570 S159 A M G E L S S S T P W H L Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519864 193 21567 A153 A L H E L I P A T T Y H V Q P
Chicken Gallus gallus P26990 175 20078 T158 V Q P S C A T T G D G L Y E G
Frog Xenopus laevis P51644 180 20567 A160 W Y V Q A T C A T Q G T G L Y
Zebra Danio Brachydanio rerio NP_956612 201 22867 H160 A L N E L G S H T P W H L Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40946 175 19987 A156 W Y V Q P S C A T S G D G L S
Honey Bee Apis mellifera XP_001120491 207 22359 S165 E L A G M P G S A C I R V Q P
Nematode Worm Caenorhab. elegans Q10943 181 20503 A160 W Y I Q A T C A T S G D G L Y
Sea Urchin Strong. purpuratus XP_785283 193 21506 L163 N V L A G C A L T G E G F E D
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 A160 W Y I Q S T C A T T G E G L Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SHU5 205 23062 T176 G L E W L S T T I P N K P E R
Baker's Yeast Sacchar. cerevisiae P11076 181 20511 A160 W F I Q A T C A T S G E G L Y
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 R154 G L S S L R Q R S W Y I Q A T
Conservation
Percent
Protein Identity: 100 89 99 60.2 N.A. 60.7 99.5 N.A. 68 42 42.5 80 N.A. 42 54.1 40 50.5
Protein Similarity: 100 90.9 99.5 80 N.A. 81 100 N.A. 85.5 58 62 89.5 N.A. 59 70.5 59.5 69.5
P-Site Identity: 100 93.3 100 40 N.A. 40 100 N.A. 46.6 0 6.6 73.3 N.A. 13.3 20 6.6 6.6
P-Site Similarity: 100 100 100 73.3 N.A. 73.3 100 N.A. 73.3 26.6 26.6 80 N.A. 26.6 40 26.6 26.6
Percent
Protein Identity: N.A. 40.5 N.A. 43.4 39.5 42
Protein Similarity: N.A. 60.5 N.A. 59.5 58 60
P-Site Identity: N.A. 6.6 N.A. 20 6.6 6.6
P-Site Similarity: N.A. 26.6 N.A. 46.6 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 0 6 6 17 17 17 45 6 0 0 0 0 6 6 % A
% Cys: 0 0 0 0 6 6 28 0 0 6 0 0 0 0 0 % C
% Asp: 0 0 0 6 0 0 0 0 0 6 0 12 0 0 6 % D
% Glu: 6 0 6 39 0 0 0 0 0 0 6 12 0 17 0 % E
% Phe: 0 6 0 0 0 0 0 0 0 0 0 0 6 0 0 % F
% Gly: 12 0 23 6 6 6 6 0 6 6 34 6 28 0 12 % G
% His: 0 0 6 0 0 0 0 6 0 0 0 45 0 0 0 % H
% Ile: 0 0 17 0 0 6 0 0 6 0 6 6 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % K
% Leu: 0 28 6 0 56 0 0 6 0 12 0 6 28 28 0 % L
% Met: 0 23 0 0 6 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 6 0 0 0 0 0 0 0 6 0 0 0 0 % N
% Pro: 0 0 6 0 6 6 6 0 0 34 0 0 6 0 39 % P
% Gln: 0 6 0 28 0 0 6 0 0 6 0 0 6 50 0 % Q
% Arg: 0 0 12 0 0 6 0 6 0 0 0 6 0 0 6 % R
% Ser: 0 0 6 12 6 34 28 28 6 17 0 0 0 0 6 % S
% Thr: 0 0 0 0 0 23 12 12 78 12 12 6 0 0 6 % T
% Val: 6 17 12 0 0 0 0 0 0 0 0 0 23 0 0 % V
% Trp: 28 0 0 6 0 0 0 0 0 6 28 0 0 0 0 % W
% Tyr: 0 23 0 0 0 0 0 0 0 0 12 0 6 0 23 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _