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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL4A All Species: 22.03
Human Site: S6 Identified Species: 28.51
UniProt: P40617 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0.12
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40617 NP_001032241.1 200 22615 S6 _ _ M G N G L S D Q T S I L S
Chimpanzee Pan troglodytes XP_001147147 220 24954 S6 _ _ M G N G L S D Q T S I L S
Rhesus Macaque Macaca mulatta XP_001099050 200 22556 S6 _ _ M G N G L S D Q T S I L S
Dog Lupus familis XP_548073 201 22148 E7 _ M G N H L T E M A P T A S S
Cat Felis silvestris
Mouse Mus musculus Q99PE9 201 22223 D7 _ M G N H L T D M A P T A S S
Rat Rattus norvegicus P61214 200 22570 S6 _ _ M G N G L S D Q T S I L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519864 193 21567 S6 _ _ V V D S I S S N I S A F Q
Chicken Gallus gallus P26990 175 20078 F9 G K V L S K I F G N K E M R I
Frog Xenopus laevis P51644 180 20567 F13 S S L F S R L F G K K Q M R I
Zebra Danio Brachydanio rerio NP_956612 201 22867 S6 _ _ M G N G L S E P H F I F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40946 175 19987 F9 G K L L S K I F G N K E M R I
Honey Bee Apis mellifera XP_001120491 207 22359 G9 G A G M G R S G T S G G F L E
Nematode Worm Caenorhab. elegans Q10943 181 20503 F13 G S L F K G L F G K R E M R I
Sea Urchin Strong. purpuratus XP_785283 193 21506 G12 F G S L L A N G Y H V V I L G
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 F13 T K L F S R L F A K K E M R I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SHU5 205 23062 L25 V R I L M V G L D G S G K T T
Baker's Yeast Sacchar. cerevisiae P11076 181 20511 S6 _ _ M G L F A S K L F S N L F
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 S6 _ _ M G N T L S I F G K L F D
Conservation
Percent
Protein Identity: 100 89 99 60.2 N.A. 60.7 99.5 N.A. 68 42 42.5 80 N.A. 42 54.1 40 50.5
Protein Similarity: 100 90.9 99.5 80 N.A. 81 100 N.A. 85.5 58 62 89.5 N.A. 59 70.5 59.5 69.5
P-Site Identity: 100 100 100 7.1 N.A. 7.1 100 N.A. 15.3 0 6.6 53.8 N.A. 0 6.6 13.3 13.3
P-Site Similarity: 100 100 100 21.4 N.A. 21.4 100 N.A. 38.4 33.3 33.3 61.5 N.A. 33.3 13.3 40 20
Percent
Protein Identity: N.A. 40.5 N.A. 43.4 39.5 42
Protein Similarity: N.A. 60.5 N.A. 59.5 58 60
P-Site Identity: N.A. 6.6 N.A. 6.6 38.4 38.4
P-Site Similarity: N.A. 33.3 N.A. 26.6 38.4 46.1
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 0 0 6 6 0 6 12 0 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 6 0 0 6 28 0 0 0 0 0 6 % D
% Glu: 0 0 0 0 0 0 0 6 6 0 0 23 0 0 6 % E
% Phe: 6 0 0 17 0 6 0 28 0 6 6 6 6 17 6 % F
% Gly: 23 6 17 39 6 34 6 12 23 6 12 12 0 0 6 % G
% His: 0 0 0 0 12 0 0 0 0 6 6 0 0 0 0 % H
% Ile: 0 0 6 0 0 0 17 0 6 0 6 0 34 0 28 % I
% Lys: 0 17 0 0 6 12 0 0 6 17 23 6 6 0 0 % K
% Leu: 0 0 23 23 12 12 50 6 0 6 0 0 6 39 0 % L
% Met: 0 12 39 6 6 0 0 0 12 0 0 0 28 0 0 % M
% Asn: 0 0 0 12 34 0 6 0 0 17 0 0 6 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 6 12 0 0 0 6 % P
% Gln: 0 0 0 0 0 0 0 0 0 23 0 6 0 0 6 % Q
% Arg: 0 6 0 0 0 17 0 0 0 0 6 0 0 28 0 % R
% Ser: 6 12 6 0 23 6 6 45 6 6 6 34 0 12 34 % S
% Thr: 6 0 0 0 0 6 12 0 6 0 23 12 0 6 6 % T
% Val: 6 0 12 6 0 6 0 0 0 0 6 6 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % Y
% Spaces: 56 45 0 0 0 0 0 0 0 0 0 0 0 0 0 % _